Thursday, 5 June 2014

Pre - Ph.D Examination Notification - August - 2014


Pre - Ph.D Examination Notification - August - 2014::

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PAPER – I Subject Code  
S. No Subject  
1 MODERN PHARMACEUTICAL ANALYTICAL TECHNIQUES 1307101  
2 ADVANCED MEDICINAL CHEMISTRY 1307102  
3 BI0-PHARMACEUTICS & PHARMACOKINETICS 1307103  
4 ADVANCED PHARMACOLOGY 1307104  
5 PHARMACEUTICAL BIOTECHNLOLOGY -I 1307105  
6 INDUSTRIAL PHARMACOGNOSY 1307106  
7 DRUG REGULATORY AFFAIRS 1307107



 
PAPER – II Subject Code  
S. No Subject  
1 ADVANCED PHARMACEUTICAL ANALYSIS 1307201  
2 ADVANCED CHEMISTRY OF NATURAL PRODUCTS 1307202  
3 ADVANCES IN DRUG DELIVERY SYSTEMS 1307203  
4 PHARMACOKINETICS AND DRUG METABOLISM 1307204  
5 PHARMACEUTICAL BIOTECHNOLOGY II 1307205  
6 HERBAL DRUG TECHNOLOGY AND FORMULATION DEVELOPMENT 1307206  
7 QUALITY ASSURANCE OF PHARMACEUT1CALS 1307207

PAPER – I

MODERN PHARMACEUTICAL ANALYTICAL TECHNIQUES

Unit I
UV-Visible spectroscopy: Introduction, electromagnetic spectrum, absorbance laws and limitations, instrumentation-design and working principle, chromophore concept, auxochromes, Wood-Fisher rules for calculating absorption maximum, applications of UV-Visible spectroscopy
Unit II
IR spectroscopy: Basic principles-Molecular vibrations, vibrational frequency, factors influencing vibrational frequencies, sampling techniques, instrumentation, interpretation of spectra, FT-IR, theory and applications
Unit III
Column Chromatography: Adsorption and partition, theory, preparation, procedure and methods of detection
Thin Layer Chromatography: Theory, preparation, procedures, detection of compounds
Paper Chromatography: Theory, different techniques employed, filter papers used, qualitative and quantitative detection
Unit IV
Gas chromatography: Introduction, fundamentals, instrumentation, columns: preparation and operation, detection, dramatization.
Unit V
HPLC: Principles and instrumentation, solvents and columns used, detection and applications
Unit VI (Research Orientation)
 Concept of quality assurance of total quality management, philosophy of GMP, CGMP, GLP and GCP
TEXT BOOKS
Instrumental Methods of Chemical Analysis by B.K Sharma
A Text book of Pharmaceutical Analysis by Kerrenth A. Connors
Quantitative Analysis of Drugs in Pharmaceutical Formulations by P. D. Sethi
Pharmaceutical Chemistry by Becket and Stanlake
Quantitative Analysis of Drugs in Pharmaceutical Formulations by P.D. Sethi
Pharmaceutical Analysis by Higuchi, Bechmman and Hassan

REFERENCES:
Organic spectroscopy by Y.R Sharma
Vogel’s Text book of Quantitative Chemical Analysis by A.I. Vogel
Practical Pharmaceutical Chemistry by A.H. Beckett and J.B. Stenlake
Organic Chemistry by I. L. Finar
Organic spectroscopy by William Kemp
Quantitative Analysis of Drugs by D. C. Garrett
Spectrophotometric identification of Organic Compounds by Silverstein
HPTLC by P.D. Seth
Indian Pharmacopoeia 2007
Remington’s Pharmaceutical Sciences by Alfonso and Gennaro
Theory and Practice of Industrial Pharmacy by Lieberman and Lachman
Indian Pharmacopoeia 1996, 2007
Instrumental Methods of Chemical Analysis By B.K. Sharma
A Text Book of Pharmaceutical Analysis by Kerrenth A. Conners
Journals (Indian Drugs, IJPS etc.)
Quality Assurance of Pharmaceuticals (A compendium of guidelines and selected materials) Vol. I& II (Pharma Book Syndicate, Book Street, Hyderabad)

ADVANCED MEDICINAL CHEMISTRY

Unit-I Theoretical Aspects of Drug Action
Types of drug action, Physicochemical parameters and pharmacological activity, Non empirical Electronic parameters, steric parameters and Stereo Chemical aspects of Drugs. Drug Receptors, Receptor types and isolation, Drug Receptor Interaction, theories of drug action, mechanism of drug action.
Unit-II Targets for the development of following chemotherapeutic agents: Anti-tubercular, Anti malarial , Anti – fungal, Immuno- modulators, Anti- amoebic drugs. Targets for the development of following pharmacodynamic agents – Antiulcer, Analgesic – Anti nflammatory, Anti atherosclerotic, Anti- Angiogenesis, anti – hypertensives.
Unit -III
Biotransformation of drugs- Prodrug approach, Soft Drug approach, enzymes responsible for biotransformation, microsomal and non microsomal mechanisms. Factors influencing enzyme induction and inhibition. Design of Local anesthetics, diuretics, Anti- HIV, anticancer, Introduction, general considerations on the development of new drugs, classical and rational procedures for the development of local anesthetics Genesis of New Drugs: Serendipity, Random Screening, Extraction of active principles from Natural Sources, Molecular Modification of Known Drugs, Selection or Synthesis of Soft Drugs, Drug Latentiation and rational drug design
Unit-IV : Rational Drug Design: QSAR: Parameters involved in QSAR, lipophilicity (Polarisabiltiy, electronic and steric parameters). Quantitative models. Hansch Analysis, Free Wilson Analysis and their relationships, linear relationships and applications of Hansch and Free Wilson Analysis. Molecular Modeling: Introduction, molecular methods, Known receptors, unknown receptors.
Unit-V: Structure based drug design : Inhibitors of HIV-I Prokinase, Structural studies of HIV-I Reverse transcriptase and implications for drug design, Bradykinin receptor Antagonists, Design of purine nucleoside and Phosphorylase inhibitors, Aldose Reductase Inhibitors, Thrombin inhibitors. Rhinoviral-Capsidbiding Inhibitors.
Unit – VI (Research Orientation)
 Design of experiments - Principles,Study of CRD,RBD,LSD and factorial designs, ANOVA
TEXT BOOKS
William O Foye Medicinal Chemistry
Berger’s Medicinal Chemistry and Drug Design. 6th Edition.
Richard B. Silvermann, Org. Chemistry of Drug Design and drug Action.
REFERENCE BOOKS
Korolkovas Essentials of Medicinal Chemistry
Purcell Strategies of Drug Design
Alfred Berger Biochemical Basis of Drug Design
Corwin , Hansen Comprehensive Medicinal Chemistry
Testa B and Jenner P. Drug Metabolism Chemical & Biochemical Aspects, Marcel Dekker
Gyorgy Keri & Istdan Toth Molecular Pathomechanism and New Trends in Drug Research, Taylor & Francis Pub.
Ariens. Drug design medicinal chemistry a series of monograph-volume 11- III, academic press, an imprint of Elsevier pub.
Structure based Drug Design by Pandi Veerapandion

BI0-PHARMACEUTICS & PHARMACOKINETICS
Unit I
Bio-availability Bioequivalence and Therapeutic equivalence: Designing of bioavailability studies and interpretation of results. Regulatory requirements.
Unit II
Physicochemical properties affecting bioavailability, pH-partition theory, dissolution, surface area adsorption, complexion, polymorphism and techniques of enhancing dissolution rate. Formulation factors affecting bioavailability of drugs in dosage forms of Tablets, capsules, parenterals, liquid orals and topical dosage forms.
Unit III
Basic concepts of Pharmacokinetics: Compartmental models: One, Two and non-compartmental approaches to Pharmacokinetics. Recent trends, merits and limitations of these approaches. Application of these models to determine the various pharmacokinetic parameters pertaining to:
a) Absorption: (wherever applicable) absorption rate constant, Absorption half time, lag time and extent of absorption, AUC.
b) Distribution: Apparent volume of distribution and its determination.
c) Metabolism: Metabolic rate constant
d) Elimination: Over all apparent elimination rate constant and half life under the following conditions:
i. Intravenous bolus injection.
ii. Intravenous infusion.
iii. Single dose oral administration.
iv. Multiple dose injections.
v. Multiple dosage oral administration
e) Non invasive methods of estimating Pharmacokinetic parameters with emphasis on   salivary and urinary compartments.
f) Concept of clearance: Organ clearance, total clearance, hepatic clearance, lung clearance and renal clearance.
Unit IV

      Non-linear Pharmacokinetics: Concepts of linear and non linear pharmacokinetics, Michaelis - Menton kinetics characteristics. Basic kinetic parameters, possible causes of non induction, non linear binding, non linearity of pharmacological responses.
Time dependent pharmacokinetics: Introduction, classification, physiologically induced time dependency: Chronopharmacokinetics, chemically induced dependency.
Unit V
      Drug Metabolism - sites of metabolism, factors affecting drug metabolism (genetic, species and environmental).
Clinical pharmacokinetics: Altered kinetics in pregnancy, child birth, infants and geriatrics. Kinetics in GI disease, malabsorption syndrome, Liver, cardiac, renal and pulmonary disease states.
Unit – VI (Research Orientation)
 Design of experiments - Principles,Study of CRD,RBD,LSD and factorial designs, ANOVA
Text Books:
1. Biopharmaceutics and clinical Pharmacokinetics by Milo Gibaldi.
2.    Remington’s Pharmaceutical Sciences by Mack publishing company, Pennsylvania.
3.    Pharmacokinetics by Milo Gibaldi, Donald Perrier; Marcel Dekker, Inc.
4.  Handbook of clinical Pharmacokinetics by Milo Gibaldi and Laurie Prescott by ADIS Health Science Press.
5.    Biopharmaceutics and Pharmacokinetics by Robert E. Notari.
6. Biopharmaceutics by Swarbrick.
7. Biopharmaceuties and Pharmacokinetics- A Treatise by D.M.Brahmankar and Sunil       B.Jaiswal., Vallabh Prakashan Pitampura, Delhi.
8. Clinical Pharmacokinetics, Concepts and Applications by Malcolm Rowland and       Thomas N.Tozer. Lea and Febiger, Philadelphia, 1995.
9. Dissolution, Bioavailability and Bioequivalence by Abdou. H.M., Mack Publishing        Company, Pennsylvania, 1989.
10. Biopharmaceutics and Clinical Pharmacokinetics- An introduction; 4th edition, Revised and expanded By Robert. E. Notari, Marcel Dekker Inc, New York and Basel, 1987.
11. Encyclopedia of Pharmaceutical Technology, Vol 13, James Swarbrick, James.       C.Boylan. Marcel Dekker Inc, New York, 1996.

ADVANCED PHARMACOLOGY

Unit-I
Molecular Pharmacology:
Pharmacology of receptors: Classification, Cellular signaling systems, and pharmacology of agonists and antagonists of the following receptors
Excitatory amino acid receptors
Purinoreceptors
GABA and Glycine receptors
Neurosteroid receptors
Cannabnoid receptors
Melatonin receptors
Adrenergic receptors
Cholinergic receptors
Dopaminergic receptors
Serotonergic receptors
Unit-II
Drugs acting on the Central Nervous System.

Drugs used in the treatment of 1. Anxiety & Depression
2. Psychosis & Mania
3. Epilepsy
4. CNS degenerative disorders
5. Parkinson’s Disease
Unit-III
Drugs affecting renal and cardiovascular function.
Diuretics
Renin & Angiotensin
Drugs used in the treatment of
Myocardial Ischemia
Hypertension
CHF
Hyperlipidemia
Anticoagulants, Thrombolytics & antiplatelet drugs.
Unit IV
Endogenous Mediators:
a)Histamine b) Prostaglandins  c) Leukotrienes, d) Nitric Oxide e) Kinins f) EDRF, EDCF & EDHF g) Opioid Peptides h) 5-HT.
Unit V
Bioassays: Basic principles of Biological standardization: Methods used in the bio-assay of Rabbis Vaccine , Oxytocin , Test for pyrogens, Test for undue toxicity
Toxicity tests:OECD guidelines. Determination of LD50, Acute, subacute and chronic toxicity studies.
Principles of clinical pharmacology and designs for testing of drugs in humans. Clinical Trials- Phases I, II, III, IV.
Stem Cells: Basic concepts and therapeutic applications in medicine.
Unit VI (Research Orientation)
Organization of screening for the Pharmacological activity of new substances with emphasis on the evaluation of psychopharmacological,anti-inflammatory, analgesic, anti diabetic, hepatoprotective, nootropic and anti cancer activities. Isolated tissues and their importance in pharmacological screening.
TEXT BOOKS:
1. Pharmacology by H.P Rang M.M, Dale, J.M.Ritter & P.K.Moore
2. The Pharmacological basis of therapeutics by Joel G.Hardman. Lee E Limbird and Alfred Goodman Gilman
3. Screening methods in Pharmacology, Vol.-1&2 by Robert .A. Turner and Peter Hebborn.
4. Basics and Clinical Pharmacology 8th edition edited by Bertram G Katzung.

REFERENCE BOOKS.
Pharmacology and Pharmacotherapeutics by R.S Satoskar, S.D Bhandarkar and S.S Ainapure.
Essentials of Medical Pharmacology by K.D.Tripathi
Drug discovery and evaluation by H.G.Vogel and W.H.Vogel, Springerverlag, Berlin Heideleberg.

Handbook of experimental pharmacology by S.K. Kulkarni, Vallabh Prakashan, Delhi.
Textbook of clinical trials edited by David Machin, Simon Day and Sylvan green.
Principles of clinical research edited by Giovanna di ignazio, Di Giovanna and Haynes

PHARMACEUTICAL BIOTECHNLOLOGY -I
Unit I
An Introduction process: The range of fermentation process, microbial biomass, microbial enzymes, microbial metabolites, recombinant products, transformation process.
Microbial growth kinetics: Batch cultures, continuous cultures, fed batch cultures, continuous with recycle culture, cascade cultures. The Isolation of industrially important micro organisms, preservation of industrially important micro organisms & improvement of industrially important micro organisms.
Unit II
Media for industrial fermentation: Introduction, types of media. Media formulation: water, carbon source, Energy source, Nitrogen source, minerals, buffers, Precursors, Inhibitors, Inducers, Antifoams, oxygen requirements. Media optimization techniques with special emphasize on statistical techniques, placket-Burman design, response surface methodology.
Sterilization: Introduction, Medium sterilization, the design of batch sterilization process, the design of continuous sterilization process, sterilization of fermented, sterilization of the feed, sterilization of liquid wastes and filter sterilization.
Unit III
The development of inocula of Industrial fermentations: Introduction, criteria for the transfer of inoculum, the development of inocula for yeast process, the development of inocula for bacterial process, the development of inocula for mycelia process, the development of inocula for vegetative fungi. The Aseptic inoculation of plant fermented.
Unit IV
Design of a Fermented: Introduction, basic function of fermenter for microbial & Animal cell culture, Aseptic operation & contaminant, overall contaminant categorization, Body construction, Aeration & Agitation, the agitators, baffles, the achievement & maintenance of aseptic condition, valves & steam traps. And other fermentation vessels.
Unit V
Applications of fermentation technology-I: Alcohol (Methanol, Butanol, Ethanol etc), Acids (citric acid, Acetic acid, Gluconic acid etc), Solvents (glycerol, Acetone, Butanol etc).
Applications of fermentation technology-II: Antibiotics (penicillin, Streptomycin, tetracycline) Amino acids (lysine, Glutamic acid), Single Cell Protein, Mineral beneficiation & Oil recovery.
Unit VI (Research Orientation)
 Concept of quality assurance of total quality management, philosophy of GMP, CGMP, GLP and GCP
TEXT BOOKS
Principles of fermentation technology by Peter F Stanbury, Allan Whitaker and Stephen J Hall, pergamon Publications.
Introduction to Biochemical Engineering by Dr. D.G. Rao, the Mc Graw Hill companies.

Industrial Pharmacognosy
Unit I
General Methods of Isolation, Purification, Identification and Estimation of Phytoconstituents.
Morphine, Quinine, Emetine, Sennosides, Volatile oils.
Unit II
Different Methods (including industrial) for the isolation and estimation of the following phytopharmaceuticals.
a) Starch b) Caffeine c) Atropine d) Taxol e) Vinca alkaloids
f) Withaferin g) Ergometrine h) Morphine.
Unit III
Applications of HPLC and HPTLC in the isolation, separation and identification of natural products with reference to the following
a) Vasicine b) Bacoposide c) Solasodine d) Lupeol.
Unit IV
Study of the following herbal extracts for processing and standardization.
a) Withania somnifera b) Ocimum sanctum c) Adathoda vasica d) Centella asiatica
e) Melia azadirachta.
Unit V
Applications of UV, IR, 1HNMR, 13CNMR and Mass Spectroscopy in the structural elucidation of natural products.
Unit VI (Research orientation)
Chromatographic applications (TLC, PC, HPLC, HPTLC, GLC) in the isolation, separation and purification of natural products.
Text Books:
1. Trease and Evans, Pharmacognosy, Latest Edition.
2. Pharmacognosy by Varro E. Lylor, Lynn R. Brody, James E. Roberts, K. M. Varghese co., Mumbai.
3. T.E. Wallis, Text Book of Pharmacognosy.
4. Diosqenin and other steroid drug precursor by asolkar, CSIR.
5. Steroids by Feiry and Feisher.
6. Alkaloids Chemical and Biological by S W Pelletier.
7. Chromatography of alkaloids by Vapoorte, Swendson.
8. Elements of chromatography by P. K. Lala.
9. Jenkins Quantitative Pharmaceutical chemistry by A. N. Knewell.
References:
1. Clarke’s Isolation and Identification of Drugs by A C Mottal.
2. Selected Topics in Exp-Pharmacology by Seth V. K.
3. Phytochemical methods of Chemical Analysis of Harborne.
4. Organic Chemistry vol. II by I. L. Finar.
5. The use of Pharmacologuical Techniques for the Evaluation of Natural Products by B.  N. Dhavan,    R. C. Srimal, CDRI Lucknow.
6. Herbal Drugs Industry by R. D. Chaudhri.
7. Herbal Pharmacopoeia.
8. HPLC methods of Drug Analysis by Mantu K Ghosh.

DRUG REGULATORY AFFAIRS

Unit I
Formulation development: Regulatory requirements involved in the preformulation studies, solid, liquid and semi-solid dosage forms, controlled release preparations, injections, ocular preparations as per the European community, United States and Indian regulatory authorities
Unit II
 Manufacturing: Regulatory requirements as per European community, United States and Indian regulatory authorities for manufacturing information, manufacturing formula, process, validation of manufacturing process, equipment, documentation, inspection requirement of regulatory guidelines for active ingredients, data requirement for new drug, International aspects of Excipients, approval as per guidelines of all the territories. Regulatory guidelines for packaging materials, test and evaluation of packaging materials, biological test, elastometer test, microbiological test and evaluation of closures.
Unit III
 Stability testing: Scientific and technical background to the design of stability testing regulatory requirements as per European community, United States and Indian regulatory authorities for testing of new active substances, bulk active drug substances, dosage form in their final packaging. Extension of shelf-life after authorization of drug international harmonization and current guidelines. Regulatory affairs in respect of residual solvents as per the ICH guidelines, analytical method validation, pharmacokinetic and toxicokinetic validation.
 Unit IV
 Preclinical aspects of Biopharmaceutics: Current guidelines and developments as per regulatory requirements of European community, United States and Indian regulatory authorities in respect of clinical bioavailability , study design, presentation documentation and statistical analysis
 Unit V
 Intellectual property rights and patents: Introduction, purpose, international scenario and Indian scenario, guidelines as per European community, United States and Indian regulatory authorities, documentation, presentation and application, procedure for obtaining and writing a patent and patenting rules and regulations
Unit VI (Research Orientation)
 Clinical pharmacology and Pharmacodynamics: Regulatory guidelines as per European community, United States and Indian regulatory authorities on clinical study design, documentation, presentation and interpretation. Clinical trials: Definition, phase I, phase II, phase III and phase IV studies, design documentation, presentation and interpretation, statistical analysis of clinical data and factorial design.

Text Books:
1. Quality Assurance Guide by Organization of Pharmaceutical producers of India.
2. Drug formulation manual by D.P.S. Kohli and D.H.Shah. Eastern publishers, New Delhi.
3. How to practice GMPs by P.P.Sharma. Vandhana Publications, Agra.
4. Pharmaceutical Process Validation by Fra. R. Berry and Robert A. Nash.
5. Pharmaceutical Preformulations by J.J. Wells.
6. Applied production and operations management by Evans, Anderson, Sweeney and Williams.
7. Basic Principles of Clinical Research and Methodology by Gupta.
8. Biopharmaceutics and Clinical Pharmacokinetics-An introduction; 4th edition, Revised and expanded by Robert. E. Notari, Marcel Dekker Inc, New York and Basel, 1987.

PAPER – II

ADVANCED PHARMACEUTICAL ANALYSIS

Unit I

Mass spectroscopy: Theory, ionization techniques: electron impact ionization, chemical ionization, field ionization, fast atom bombardment, plasma desorption, fragmentation process: types of fission, resolution.
Unit II
GC/MS, interpretation of spectra and applications for identification and structure determination
Unit III
NMR: Theory, instrumentation, chemical shift, shielding and deshielding effects, splitting of signals,
spin-spin coupling, proton exchange reactions, coupling constant(J), nuclear overhauser effect(NOE), 13C NMR spectra and its applications, 2D-NMR, COSY and applications in pharmacy
Unit IV
Counter – current extraction, solid phase extraction techniques, gel filtration.
An advanced study of the principles and procedures involved in the electrometric methods: Coductometry, Potentiometry, and Polarography and Amperometry.
Unit V
Principles and procedures involved in using the following reagents in pharmaceutical analysis with suitable examples
MBTH (3-methyl-2- benzothizolone hydrazone)
F.C. Reagent (Folin-Ciocalteau)
PDAB (Para Dimethyl Amino Benzaldehyde)
2, 3, 5 – Triphenyl tetrazolium salt
2,6 Dichloroquinone Chlorimide
Unit VI (Research Orientation)
Concepts of Analytical Method Development, validation and calibration of various Analytical Instruments such as UV and visible spectrophotometer, Spectrofluorimenter, HPLC and GC-MS and analytical methods

TEXT BOOKS
Instrumental Methods of Chemical Analysis by B.K Sharma
A Text book of Pharmaceutical Analysis by Kerrenth A. Connors
Quantitative Analysis of Drugs in Pharmaceutical Formulations by P. D. Sethi
Pharmaceutical Chemistry by Becket and Stanlake
Quantitative Analysis of Drugs in Pharmaceutical Formulations by P.D. Sethi
Pharmaceutical Analysis by Higuchi, Bechmman and Hassan


REFERENCES:
Organic spectroscopy by Y.R Sharma
Vogel’s Text book of Quantitative Chemical Analysis by A.I. Vogel
Practical Pharmaceutical Chemistry by A.H. Beckett and J.B. Stenlake
Organic Chemistry by I. L. Finar
Organic spectroscopy by William Kemp
Quantitative Analysis of Drugs by D. C. Garrett
Spectrophotometric identification of Organic Compounds by Silverstein
HPTLC by P.D. Seth
Indian Pharmacopoeia 2007
Remington’s Pharmaceutical Sciences by Alfonso and Gennaro
Theory and Practice of Industrial Pharmacy by Lieberman and Lachman
Indian Pharmacopoeia 1996, 2007
Instrumental Methods of Chemical Analysis By B.K. Sharma
A Text Book of Pharmaceutical Analysis by Kerrenth A. Conners
Journals (Indian Drugs, IJPS etc.)
Quality Assurance of Pharmaceuticals (A compendium of guidelines and selected materials) Vol. I& II (Pharma Book Syndicate, Book Street, Hyderabad)

ADVANCED CHEMISTRY OF NATURAL PRODUCTS

Unit I
     (A) General Methods of Extraction, Qualitative chemical test for the detection of various
             natural product compounds.
(B) Study of herbal extracts – processing, equipment and analytical profile of extracts of
      drugs.
Unit II
Isolation/Separation techniques – The technique and application of thin layer chromatography and preparative TLC, column chromatography – medium and high-pressure liquid column chromatography, flash chromatography, HPTLC, HPLC and GC – normal and reverse phase techniques.
Unit III

Alkaloids - Introduction, general methods of structure elucidation, chemistry and structure elucidation of morphine, reserpine and quinine. Isolation procedure of piperine and quinine.
Unit IV

Steroids – Introduction, nomenclature and stereochemistry, chemistry of cardiac glycosides, progesterone, oestradiol, cortisone, testosterone, bile acids, chemistry and structure elucidation of cholesterol, testosterone, progesterone. Synthesis of stilbesterol & hexesterol Isolation procedure of diosgenin and sennosides.
Unit V

Natural Products as Leads for New DrugsIntroduction/History, approaches to discovery and development of natural products as potential new drugs, selection and optimization of lead compounds for further developments from CNS, anti cancer, antibiotic and cardiovascular drugs.
Unit VI (Research Orientation)
Organization of screening for the Pharmacological activity of new substances with emphasis on the evaluation of psychopharmacological,anti-inflammatory, analgesic, anti diabetic, hepatoprotective, nootropic and anti cancer activities. Isolated tissues and their importance in pharmacological screening.
Text Books
Organic Chemistry Vol. 2nd by I. L. Finar
Org. Chemistry by Morrison & Boyd
Alkaloids – Chemical & Biological Prospective by S. W. Pelletier
Steroids by Fischer and Fischer
References:
Pharmacognosy by Trease & Evans
Chemistry of Natural Products – Ata Ur Rehman
Natural Products – A Lab Guide by Raphael Ikon
Screening methods in Pharmacology, Vol.-1&2 by Robert .A. Turner and Peter Hebborn.

ADVANCES IN DRUG DELIVERY SYSTEMS
Unit I
Fundamentals of controlled drug delivery systems, use of polymers in controlled drug delivery, pharmacokinetic and pharmacodynamic basis of controlled drug delivery. Factors involved and regulatory requirements
Unit II

Design, fabrication, evaluation and applications of the following controlled release systems.
a) Controlled release oral drug delivery systems
b) Parenteral controlled release drug delivery systems
c) Implantable therapeutic systems
Unit III
d)Transdermal therapeutic systems and Iontophoresis
e) Ocular and intrauterine delivery systems
f) Bioadhesive drug delivery systems
g) Proteins and peptide drug delivery
Unit IV

Biochemical and molecular biology approaches to controlled drug delivery
a) Micro particulate drug carriers; Liposomes, Niosomes, Microspheres, Nanoparticles
and Resealed erythrocytes.
b) Monocional antibodies
Unit V
Drug targeting to particular organs:
a) Drug delivery to respiratory system
b) Problems of drug delivery to the brain and targeting to brain
c) Drug delivery to eye
d) Drug targeting in Neoplastic diseases
Unit VI (Research Orientation)
 Concept of quality assurance of total quality management, philosophy of GMP, CGMP, GLP and GCP
Text Books:
1.   Encyclopedia of controlled delivery; by Edith Mathiowitz, Published by Wiley Interscience Publication, John Wiley and sons, Inc, New York / Chichester / Weinheim.
2. Controlled and Novel Drug Delivery by N.K.Jain, CBS Publishers and Distributors, New Delhi, First edition, 1997 (reprint in 2001).
3. Controlled Drug Delivery - Concepts and Advances by S.P.Vyas and R.K.Khar, Vallabh Prakashan, New Delhi, First edition, 2002.
4. Remington’s Pharmaceutical Sciences.
5. Novel drug delivery system by Y.M.Chien, Marcel Dekker, Inc.
6. Controlled Drug Delivery - Fundamentals and Applications, 2nd edition by Joseph R.Robinson and Vincent H.L.Lee.
7. Pharmaceutical Dosage forms, disperse system: Volume 1, by Herbert A.Libermann et.al, Marcel Dekker, Inc.
8. Pharmaceutical Dosage forms: Tablets Volume II, Herbert A.Libermann et.al, Marcer Dekker, Inc.
9. Bentley’s Textbook of Pharmaceutics by E.A.Rawline, ELBS Publications.
10. Microencapsulation and Related Drug Process by Patric B.Deasy.

Pharmacokinetics and Drug Metabolism

Unit -I
Drug Absorption: Gastrointestinal, percutaneous and rectal kinetics and factors affecting drug absorption.
Unit -II
Drug distribution: plasma protein binding – factors affecting plasma protein binding – Tissue binding – transfer of drugs through biological barriers their therapeutic implication in drug action.
Elimination of drugs: Concept of renal clearance and excretion of drugs – biological half-life.
Unit -III
Bioavailability of   drug products: Bioavailability tests. Reaction of the body to foreign substances: Biotransformation of drugs, phase I and phase II metabolic reactions.
Unit -IV
Microsomal and non-microsomal biotransformation reactions. Drug metabolism in liver, kidney, intestine and placenta. Drug metabolism in fetus and new born. In-Vitro and In-Vivo studies in drug metabolism; metabolic schemes of selected drugs.
Unit -V
Factors influencing drug metabolism: (1) Steriochemical, Physico-chemical  and biological factors, (2) Physiological: Species difference, strain difference, sex, age, environment factors, (3) Pathological states, (4) Genetic factors – Pharmacogenetics – heritable factors recognized in man by use of drugs.
Drug interactions: Pharmacokinetic, Pharmacodynamic drug interactions, Food drug and drink interactions.
Unit – VI (Research Orientation)
 Design of experiments - Principles,Study of CRD,RBD,LSD and factorial designs, ANOVA

Text Books :
1. Gibaldi, M. and Donald Perrier – Pharmacokinetics  Page No. 29/43
2. Rowland, M. and Tozer, T.N. , Clinical Pharmacokinetics – Concepts and applications,           Lea and Fibiger, USA
3. Abdou, H.M., Dissolution, Bioavailability and Bioequivalence, Mack Publishing Co. Ltd., Easton, PA
4. Applied Biopharmaceutics and Pharmacokinetics by Leon Shargel, Susanna WU – Pong & Andrew B.C. Yu
5. Principles of Medicinal Chemistry by William O. Foye, Thomas L. Lemke and David A. Williams
6. Wilson and Gisvold’s text book of Organic Medicinal and Pharmaceutical Chemistry by Jaime N. Delgado & William A. Remers
References:
1. The Pharmacological basis of therapeutics by Joel G. Hardman, Lee E. Limbird and Alfred Goodman Gilman
2. Principles of Medicinal Chemistry by William O. Foye, Tomas L. Lemke & David A. Williams
3. Pharmacology by H.P. Rang, M.M. Dale, J.M. Ritter & P.K. Moore
4. Essentials of Pharmacotherapeutics by F.S.K.Barar
5. Principles of drug action by Golsteins, Aranow and Kalman.

PHARMACEUTICAL BIOTECHNOLOGY II

Unit I.
Enzymes: Classification and nomenclature, mode and mechanism of enzyme action. Pharmaceutical
Applications of enzymes. Bacterial enzymes, industrial enzymes and production of enzymes. Study of
Pharmaceutical and therapeutic enzyme.
Unit - II
Immobilization: Various techniques, immobilization of cells and enzymes. Applications of Immobilization -
enzyme and cell immobilization, its therapeutic applications.
Unit - III
 Genetics: Structure of DNA as genetic materiel, Replication, repair, gene rearrangements, recombination
and transposition, RNA synthesis and splicing. Protein synthesis and targeting. Control of gene
expression in prokaryotes. Eukaryotic chromosomes and gene expressions.
Unit - IV
 Recombinant DNA technology: Introduction, mutagenesis, cutting and rejoining. Polymerase chain
reaction,. Isolation and amplication of genes, gene expression genetic recombination: Transfer of
characters, genetic recombination, phage crosses, and gene transfer mechanism.
Unit -V
Immunology, Monoclonal antibodies and Hybridoma technology: A brief introduction to immunology.
Formation and selection of hybrid cells,principles and productions of monoclonal antibodies,commercial
production, characterisation, quality control and storage of monoclonal antibodies. Advantages and
applications of monoclonal antibodies.
Unit – VI (Research Orientation)
 Tissue culture: Introduction, historical background, preparation of culture media, types of culture,
modification through transformative cell culture, Regeneration of plants. Micropropagation,
protoplast microinjection Methods of gene transfer in plants, pharmaceutical applications of plant tissue
culture.
BOOKS RECOMMENDED:
1. Pharmaceutical Biotechnology: Vyas and Dixit.
2. Gene VII: Lewin Benzamin.
3. Industrial Microbiology: L.E. Casida.
4. Biotechnology- The Biological Principles: M.D. Trevan, S. Boffey, K.H. Goulding and P. Stanbury.
5. Microbial Genetics: David Freifelder.
6. Immunology: J. Kuby.
7. Immunology: Weir.

Herbal Drug Technology and Formulation Development

Unit I
Tissue culture: a) Culture methods b) Organogenesis and embryogenesis
c) Micro propagation      d) Haploid culture e) Synthetic seeds f) Immobilization
.
Unit II
Production of secondary metabolites:
Strategies, use of precursors, growth regulators and elicitors, batch culture and continuous culture, application of new culture method, hair root culture, biotransformation, production of secondary metabolites, taxol, ajmalcine, artemicin.

Unit III
Mutations, Hybridization, Polyploidy of Medicinal Plant and their application.

Unit IV
Biogenesis of penicillin streptomycin and tetracyclines.

Unit V
Manufacturing of  the following phytopharmaceuticals.
a) Strychnine b) Emetin c) Quinine d) Morphine e) Cocaine f) Atropine.

Unit VI (Research Orientation)
Concept of quality assurance , total quality management, philosophy of GMP, CGMP, GLP and GCP


Text Books:
Quality control methods of Herbal Drugs by Pulok. V. Mukherjee.
Trease and Evans, Pharmacognosy, Latest Edition.
3. T.E. Wallis, Text Book of Pharmacognosy.
4. Diosqenin and other steroid drug precursor by asolkar, CSIR.
5. Steroids by Feiry and Feisher.
6. Alkaloids Chemical and Biological by S W Pelletier.
7. Chromatography of alkaloids by Vapoorte, Swendson.
8. Elements of chromatography by P. K. Lala.
9. Jenkins Quantitative Pharmaceutical chemistry by A. N. Knewell.
10. Pharmacognosy by Varro E. Lylor, Lynn R. Brody, James E. Roberts, K. M. Varghese co., Mumbai.
References:
1. Clarke’s Isolation and Identification of Drugs by A C Mottal.
2. Selected Topics in Exp-Pharmacology by Seth V. K.
3. Phytochemical methods of Chemical Analysis of Harborne.
4. Organic Chemistry vol. II by I. L. Finar.
5. The use of Pharmacologuical Techniques for the Evaluation of Natural Products by B.  N. Dhavan,    R. C. Srimal, CDRI Lucknow.
6. Herbal Drugs Industry by R. D. Chaudhri.
7. Herbal Pharmacopoeia.
8. HPLC methods of Drug Analysis by Mantu K Ghosh.

QUALITY ASSURANCE OF PHARMACEUT1CALS

Unit I
     Concept of Quality assurance, total quality management, philosophy of GMP,   CGMP andGLP.
     Organization and personnel, responsibilities, training hygiene - Premises: Location, design, plan layout, construction, maintenance and sanitations, environmental control, sterile areas, control of contamination.
Unit II
     Equipments: Selection, purchase specifications, maintenance, clean in place, sterilize in place - Raw materials: Purchase specifications, maintenance of stores, selection of vendors, controls and raw materials.
Unit III
     Manufacture and controls on dosage forms, manufacturing documents master formula, batch formula records, standard operating procedures, quality audits of manufacturing processes and facilities - In process quality control on various dosage forms: sterile, biological products and non sterile, standard operating procedures for various operations like cleaning, filling, drying, compression, coating, disinfection, sterilization, membrane filtration etc.
Unit IV
Guidelines for Quality Assurance of Human Blood products and large volume parenterals.
     Packaging and labeling controls, line clearance and other packaging materials.
   
Unit - V
     Distribution and Distribution records: Handling of returned goods, recovered materials and reprocessing.
    Complaints and recalls, evaluation of complaints, recall procedures, related records and documents.
Unit – VI (Research Orientation)
     Quality Control Laboratory: Responsibilities, good laboratory practices, routine controls, instruments, protocols, non-clinical testing, controls on animal house, data generation and storage, quality control documents, retention samples, records, audits of quality control facilities - Finished products release: quality review, quality audits, and batch release document
TEXT BOOKS
1. The International Pharmacopoeia Vol. 1,2,3,4, 3rd edition General methods of analysis quality specifications for Pharmaceutical substances, Excipients, dosage forms.
2. Quality Assurance of Pharmaceuticals: A compendium of guidelines and related material Vol. 1 and Vol. 2., WHO, (1999).
3. GMP-Mehra
4. Pharmaceutical Process validation by Berry and Nash
REFERENCE BOOKS
1. Basic tests for Pharmaceutical substances - WHO (1988)
2. Basic tests for Pharmaceutical substances - WHO (1991)
3. How to practice GMP’s – P.P.Sharma
4. The Drugs and Cosmetic Act 1940- Vijay Malik
5. Q.A Mannual by D.H.Shah
6. SOP Guidelines by D.H.Shah
7. Quality Assurance Guide by OPPI

Pre - Ph.D Examination Notification - August - 2014


Pre - Ph.D Examination Notification - August - 2014::

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PAPER – I Subject Code  
S. No Subject  
1 Mechanics of Composite Materials 1303101  
2 Design of Mechanisms and Manipulators 1303102  
3 Failure Analysis and Design 1303103  
4 Acoustics Engineering 1303104  
5 Signal Analysis and Condition Monitoring 1303105  
6 Bearing Design & Rotor Dynamics 1303106  
7 Fracture Mechanics 1303107  
8 Fuels, combustion & Environmental Pollution Control 1303108  
9 Convective Heat & Mass Transfer 1303109  
10 Advanced Thermodynamics 1303110  
11 Computational Methods in Thermal Engineering 1303111  
12 Thermal Systems Simulation & Design 1303112  
13 Combustion & Emission in Engines 1303113  
14 Computational Fluid Dynamics 1303114  
15 Advanced Optimization Techniques 1303115  
16 Theory of Metal Cutting & Tool Design 1303116  
17 Metal Forming Processes 1303117  
18 Rapid Prototyping & Tooling 1303118  
19 Non-Destructive Evaluation 1303119  
20 Quality Engineering and Manufacturing 1303120  
21 Mechanics and Manufacturing Methods of Composites 1303121







PAPER – II Subject Code  
S. No Subject  
1 CAD Theory & Practice 1303201  
2 Experimental Stress Analysis 1303202  
3 Advanced Mechanical Vibrations 1303203  
4 Simulation and Modeling 1303204  
5 Design of Hydraulic & Pneumatic Systems 1303205  
6 Design of Pumps and Compressors 1303206  
7 Theory of Plasticity 1303207  
8 Electric & Hybrid Vehicles 1303208  
9 Design of Heat Transfer Equipment 1303209  
10 Refrigeration Equipment & Controls 1303210  
11 IC Engines & Alternative Fuels 1303211  
12 Thermal & Nuclear Power Plants 1303212  
13 Experimental Methods in Thermal Engineering 1303213  
14 Electronic Engine Management Systems 1303214  
15 Intelligent Manufacturing Systems 1303215  
16 Logistics & Supply Chain Management 1303216  
17 Advances in Manufacturing Technology 1303217  
18 Production & Operations Management 1303218  
19 Advances in Casting & Welding Processes 1303219  
20 Materials Technology 1303220  
21 Statistical Quality Control 1303221
PAPER – I
MECHANICS OF COMPOSITE MATERIALS

UNIT I
Basic concepts and characteristics: Geometric and Physical definitions, natural and man-made composites, Aerospace and structural applications, types and classification of composites.
Reinforcements: Fibres- Glass, Silica, Kevlar, carbon, boron, silicon carbide, and born carbide fibres. Particulate composites, Polymer composites, Thermoplastics, Thermosetts, Metal matrix and ceramic composites.

UNIT II
 Micromechanics: Unidirectional composites, constituent materials and properties, elastic properties of a lamina, properties of typical composite materials, laminate characteristics and configurations. Characterization of composite properties.
UNIT III
 Coordinate transformations: Hooke’s law for different types of materials, Hooke’s law for two dimensional unidirectional lamina, Transformation of stress and strain, Numerical examples of stress strain transformation, Graphic interpretation of stress – strain relations. Off - axis, stiffness modulus, off - axis compliance.

UNIT IV
 Elastic behavior of unidirectional composites: Elastic constants of lamina, relationship between engineering constants and reduced stiffness and compliances, analysis of laminated composites, constitutive relations.
Strength of unidirectional lamina: Micro mechanics of failure, Failure mechanisms, Strength of an orthotropic lamina, Strength of a lamina under tension and shear maximum stress and strain criteria, application to design. The failure envelope, first ply failure, free-edge effects. Micro mechanical predictions of elastic constants.

UNIT V
Analysis of laminated composite plates
Introduction, thin plate theory, specially orthotropic plate, cross and angle ply laminated plates, problems using thin plate theory.
Manufacturing methods: Autoclave, tape production, moulding methods, filament winding, man layup, pultrusion, RTM.

Suggested Assignment:
To refer ASTM Series of Journal of composites, Technology and Research for giving a seminar on any current topic of relevance.

REFERENCE BOOKS:
1. R. M. Jones, Mechanics of Composite Materials, Mc Graw Hill Company, New York.
2. Engineering Mechanics of Composite Materials by Isaac and M.Daniel, Oxford
University Press.
3. B. D. Agarwal and L. J. Broutman, Analysis and performance of fibre Composites,
Wiley-Interscience, New York.
4. L. R. Calcote, Analysis of Laminated Composite Structures, Van Nostrand Rainfold
DESIGN OF MECHANISMS AND MANIPULATORS
UNIT I
Mobility analysis, Degree of freedom, Mixed mobility, Total, partial and fractional DOF, Closed and open chain systems, Structural analysis and synthesis of mechanisms.

UNIT II
Alternative design solutions, Coding, Evaluation and selection of optimum mechanism, Type synthesis, Number synthesis, and design of mechanisms,

UNIT III
Indexes of merit, Graphical, Algebraic and optimization techniques, Matrix method of design and analysis, Design of function path and motion generators, Structural and mechanical error,

UNIT IV
Design and analysis using software like ADAMS. Design of Manipulators: Classification, Actuation and transmission systems, Co-ordinate transformations, DH notations.

UNIT V
Inverse and forward kinematics, Manipulators dynamics from Lagrangian and Newtonian point of view.

Suggested Assignment:
To refer ASME Series of Journal of Mechanism and Robotics, Journal of Mechanical Design for giving a seminar on any current topic of relevance.

Text Books:
1.Robot Design Handbook G.B. Andeen McGraw Hill
2.Introduction to Robotics, Mechanics and Control J.J. Craig Addison Wesley
3.Robotic Manipulators: Mathematics, Programming and Control R.P. Paul MIT Press
4.Robot Dynamics and Control M. Spong and M.Vidyasagar, JohnWiley, NY
5.Dextrous Robot Hands S.T. Venkataraman Springer-Verlag


FAILURE ANALYSIS AND DESIGN

Unit I
Role of Failure Prevention Analysis in Mechanical Design: Introduction, a definition of design, a challenge, some design objectives. Modes of Mechanical Failure: Definition of failure mode, failure modes observed in practice, a glossary of mechanical failure modes. Introduction to Fracture Mechanics: An introduction to linear elastic fracture mechanics, use of fracture mechanics design, elastic-plastic fracture mechanics.

Unit II
High-Cycle Fatigue: Introduction, historical remarks, nature of fatigue, fatigue loading, laboratory fatigue testing, the S-N-P curves, factors that affect S-N-P curves, using the factors in design, the influence of nonzero mean stress, multiaxial fatigue stresses, using multiaxial fatigue failure theories.

Unit III
Cumulative Damage, Life Prediction and Fracture Control: Introduction, the Linear damage theory, cumulative damage theories, life prediction based on local stress-strain and fracture mechanics concepts, service loading simulation and full scale fatigue testing, damage tolerance and fracture control.

Unit IV
Low-Cycle Fatigue: Introduction, the strain cycling concept, the strain life curve and low-cycle fatigue relationships, the influence of nonzero mean strain and nonzero mean stress, cumulative damage rule in low-cycle fatigue. Creep, Stress Rupture and Fatigue: Introduction, prediction of long-term creep behavior, theories for predicting creep behavior, creep under uniaxial state of stress and multi axial state of stress, cumulative creep concept, combined creep and fatigue.

Unit V
Fretting, Fretting Fatigue and Fretting Wear: Introduction, variables of importance in the fretting process, fretting fatigue, fretting wear, fretting corrosion, minimizing or preventing fretting damage. Wear and Corrosion: Introduction, wear – Adhesive, abrasive, corrosion, surface fatigue, deformation, fretting, impact, empirical model of zero wear, corrosion, stress corrosion cracking.

Suggested Assignment:
To refer ASME Series of Journal of Mechanism and Robotics, Journal of Mechanical Design for giving a seminar on any current topic of relevance.

Text book:
1. Failure of Materials in Mechanical Design: Analysis, Prediction, Prevention, J. A. Collins, John Wiley & Sons, Inc.

References:
1. Fatigue of Materials, S. Suresh, Cambridge University Press.
2. Fracture Mechanics: Fundamentals and Applications, T. L. Anderson, CRC Press.


ACOUSTICS ENGINEERING
UNIT I
Introduction to the propagation of acoustic disturbances: Longitudinal wave motion. Introduction to plane wave acoustics. Sound speed, frequency, wavelength, wavenumber. Acoustic impedance. Thermodynamics of acoustic pressure perturbations. Acoustic energy density. Acoustic intensity.
UNIT II
One-dimensional wave motion
Mass continuity and momentum conservation equations in one dimension. Linearization of the governing equation and the derivation of the one-dimensional wave equation. Solutions to the one dimensional wave equation. Linearity and the principle of superposition. Energy density and intensity.
UNIT III
Waves in three dimensions
Conservation equations in three dimensions. The three dimensional wave equation and its solution in free field. Spherically symmetric radiation. Acoustic impedance of spherical waves.

UNIT IV
Sound Radiation
The pulsating sphere. The point monopole source. Source strength. Acoustic power output. Monopole source radiation in the vicinity of a perfectly rigid plane boundary. Radiation from a plane vibrating piston. Near field and far field. Radiation impedance. Radiation efficiency of spherical sources.
UNIT V
Sound field in rooms
Separable solutions to the three dimensional wave equation. Eigen functions and Eigen values. Direct fields and reverberation.
Suggested Assignment:
To refer ASME Series of Journal of Vibration and Acoustics for giving a seminar on any current topic of relevance.


TEXT BOOKS:
Foundations of Engineering Acoustics by FGrank J Fahy, Elsevier Academic Press
Foundations of Engineering Acoustics by Lawrence E Kinsler, John Wiley
Acoustics an Introduction by Heinrich Kuttruff, Taylor Francis group Publishers
Fundamentals of Physical Acoustics by David T. Blackstock, John Wiley Publishers
Fundamentals of Acoustics by Michel Bruneau, ISTE Publishers, USA.




SIGNAL ANALYSIS AND CONDITION MONITORING
UNIT-I
Introduction: Basic concepts. Fourier analysis. Bandwidth. Signal types. Convolution. Signal analysis: Filter response time. Detectors. Recorders. Analog analyzer types.

UNIT-II
Practical analysis of stationary signals: Stepped filter analysis. Swept filter analysis. High speed analysis. Real-time analysis.

UNIT-III
Practical analysis of continuous non-stationary signals: Choice of window type. Choice of window length. Choice of incremental step. Practical details. Scaling of the results.

UNIT-IV
Practical analysis of transients: Analysis as a periodic signal. Analysis by repeated playback (constant bandwidth). Analysis by repeated playback (variable bandwidth).

UNIT-V
Condition monitoring in real systems: Diagnostic tools. Condition monitoring of two stage compressor. Cement mill foundation. I.D. fan. Sugar centrifugal. Cooling tower fan. Air separator. Preheater fan. Field balancing of rotors. ISO standards on vibrations.

Suggested Assignment:
To refer ASME Series of Journal of Tribology for giving a seminar on any current topic of relevance.

Text Book:
1. Condition Monitoring of Mechanical Systems by Kolacat

References:
1. Frequency Analysis by R.B.Randall. Bruel Kjaer, 3rd Ed. 1987
2. Mechanical Vibrations Practice with Basic Theory by V. Ramamurti, Narosa Publishing House.

BEARING DESIGN AND ROTOR DYNAMICS

UNIT I
CLASSIFICATION AND SELECTION OF BEARINGS                      
Selection criteria-Dry and Boundary Lubrication Bearings-Hydrodynamic and Hydrostatic bearings- Electro Magnetic bearings-Dry bearings-Rolling Element bearings- Bearings for Precision Applications-Foil Bearings-Special bearings- Selection of plain Bearing materials –Metallic and Non metallic bearings
UNIT II
DESIGN OF FLUID FILM BEARINGS                                              
Design and performance analysis of Thrust and Journal bearings – Full, partial, fixed and pivoted journal bearings design procedure-Minimum film thickness – lubricant flow and delivery – power loss, Heat and temperature distribution calculations- Design based on Charts & Tables and Experimental curves-Design of Foil bearings-Air Bearings- Design of Hydrostatic bearings-Thrust and Journal bearings- Stiffness consideration - flow regulators and pump design
UNIT III
SELECTION AND DESIGN OF ROLLING BEARINGS                  
Contact Stresses in Rolling bearings- Centrifugal stresses-Elasto hydrodynamic lubrication- Fatique life calculations- Bearing operating temperature- Lubrication- Selection  of lubricants- Internal clearance – Shaft and housing fit- -Mounting arrangements-Materials for rolling bearings- Manufacturing methods- Ceramic bearings-Rolling bearing cages-bearing seals selection
UNIT IV
DYNAMICS OF HYDRODYNAMIC BEARINGS    
Hydrodynamic Lubrication equation for dynamic loadings-Squeeze film effects in journal bearings and thrust bearings -Rotating loads , alternating and impulse loads in journal bearings – Journal centre Trajectory- Analysis of short bearings under dynamic conditions- Finite difference solution for dynamic conditions
UNIT V
ROTOR DYNAMICS
Rotor vibration and Rotor critical speeds- support stiffness on critical speeds- Stiffness and damping coefficients of journal bearings-computation and measurements of journal bearing coefficients -Mechanics of Hydro dynamic Instability- Half frequency whirl and Resonance whip- Design configurations of stable journal bearings                                                                                                                

Suggested Assignment:
To refer ASME Series of Journal of Tribology, Journal of Mechanical Design for giving a seminar on any current topic of relevance.

REFERENCES:                                                                                              
1.Neale, M.J.  “Tribology Hand Book”,   Butterworth Heinemann, United Kingdom 2001.
Cameron, A. “Basic Lubrication Theory”, Ellis Herward Ltd., UK, 1981
Halling, J.  (Editor) – “Principles of Tribology “,  Macmillian – 1984.
Williams J.A. “ Engineering Tribology”,  Oxford Univ. Press, 1994.
S.K.Basu, S.N.Sengupta & B.B.Ahuja ,”Fundamentals of Tribology”, Prentice –Hall of India Pvt  Ltd , New Delhi, 2005
G.W.Stachowiak & A.W .Batchelor , Engineering Tribology, Butterworth-Heinemann, UK,  2005

FRACTURE MECHANICS

UNIT I
Introduction sources of micro and macro cracks fracture criterion based on stress concentration and theoretical strength Griffith’s energy - various approach - Stress Analysis
for Members with Cracks.

UNIT II
Crack tip Plastic Zone: Plastic zone estimation - yielding fracture mechanics.

UNIT III
Elastic–Plastic Fracture Mechanics - Path-independent integrals, J-integral , J-integral fracture criterion, crack opening displacement(COD), experimental determination of Jintegral
and COD - Fatigue and Fatigue crack growth rate.

UNIT IV
Linear static fracture Mechanics Design Concepts - Introduction, the stress criterion, strain
energy density, 2-D linear elastic crack problems.

UNIT V
Dynamic Fracture: Mohr’s model, strain energy release rates, crack branching, practical
applications of crack arresting techniques. Experimental determination of dynamic SIF. -
NDT and Fracture Mechanics

Suggested Assignment:
To refer Springer Publishers International Journal of Fracture for giving a seminar on any current topic of relevance.


REFERENCES
1. S.A. Maguid,, “Engineering Fracture Mechanics”, Elsevier, 1996
2. David Broke., “Elementary Engineering Fracture Mechanics”, Noordhoff, 1995.
3. Karen Hellan, “Introduction to Fracture Mechanics”, Mc Graw Hill, 1982.

FUELS, COMBUSTION AND ENVIRONMENTAL POLLUTION CONTROL

UNIT I
Fuels:- Detailed classification-Conventional and unconventional, solid, liquid, gaseous fuels – Coal-carbonization, Gasification and liquefaction – Lignite; Petroleum based fuels- problems associated with low calorific value gases. Coal gas, Blast furnace gas, Alcohols, Biogas and Nuclear fuels.

UNIT II
Principles of Combustion:- Chemical kinetics – Adiabatic flame temperature – Laminar and turbulent flame propagation and structure – Flame stability – Combustion of fuel droplets and sprays – Combustion systems – pulverized fuel furnaces – Fixed, entrained and fluidized bed systems.

UNIT III
Environmental considerations:- Air pollution – Effects on environment, human health, etc., Principal pollutants – Legislative measures – Methods of emission control. Environmental segments, Natural cycles of environment, Atmospheric structure, Green house effect, Ozone hole, Effect of pollution on living systems, Minimum national standards.

UNIT IV
AIR POLLUTION -Sources and classification of pollutants, Effect of air pollution, Pollution from industries, Chemical reactions in a contaminated atmosphere, urban air pollution, Acid rain, Photo chemical smog, Meteorological aspects of air pollution. Air pollution sampling and measurement, Air pollution control methods and equipment.

UNIT V
WATER POLLUTION AND CONTROL - Origin of waste water, Types of water pollutants and their effects ,Water pollution laws and standards Waste water sampling and analysis , Treatment of waste water.
SOLID WASTE MANAGEMENT - Sources and classification, Public health aspects, methods of collection, Disposal methods, Potential methods of disposal.
NOISE POLLUTION - Human acoustics, Sound and its general features, Noise and its measurement, Noise pollution hazards & Controlling methods.

Suggested Assignment:
To refer Elsevier Publishers International Journal of Environmental Pollution, Inder Science Publishers International Journal of Environment and Pollution for giving a seminar on any current topic of relevance.

TEXTBOOKS:
1. Combustion Fundamentals by Roger A. Strehlow – Mc.Graw Hill
2. Fuels and Combustion by Sharma and Chander Mohan – Tata Mc.Graw Hill.
3. Combustion Engineering and fuel Technology by Shaha A.K. – Oxford and IBH.
4. Principles of Combustion by Kenneth K. Kou – wiley & Sons.
5. Pollution control in process industries - S.P. Mahajan/Tata Mc Graw Hill
6. Environmental pollution control engineering - C.S.Rao/New age Int. Pvt.Ltd
7. Air pollution - M.N.Rao and M.V.N.Rao /Tata Mc Graw Hill
8. Energy Technology - S.Rao and B.B.Parulekar /Khanna publishers

CONVECTIVE HEAT & MASS TRANSFER
UNIT I
Introduction to convection, review of conservation equations - Forced convection in laminar flow - Exact and approximate solutions of Boundary layer energy equation for plane isothermal plate in longitudinal flow - problems. Forced convection heat transfer in laminar tube flow - forced convection in turbulent flow – Internal Flows-Correlations-Problems.

UNIT II
Approximate analysis of laminar free convective heat transfer on a vertical plate-external flows-correlations-problems. Boiling and condensation: Analysis of film condensation on a vertical surface – pool boiling - forced convection boiling inside tubes - problems.

UNIT III
Definitions of concentration and velocities relevant to mass transfer, Fick's law, species conservation equation in different forms. Steady state diffusion in dilute solutions in stationary media, transient diffusion in dilute solutions in stationary media, one dimensional non dilute diffusion in gases with one component stationary.

UNIT IV
Convective mass transfer - governing equations-forced diffusion from flat plate- Dimension less correlation’s for mass transfer.

UNIT V
Simultaneous heat and mass transfer - analogy between heat, mass and momentum transfer.

Suggested Assignment:
To refer ASME Series of Journal of Heat Transfer for giving a seminar on any current topic of relevance.

REFERENCES:
1. Heat transfer - J. P. Holman.
2. Heat and Mass transfer- R.C. Sachdeva
3. Convective Heat and Mass transfer-Kays.
4. Heat and Mass transfer - V.Gupta and I.Srinivasan - Tata Mc.Graw Hill

ADVANCED THERMODYNAMICS

UNIT I
BASIC CONCEPTS: Thermodynamics - Temperature and zeroth law of thermodynamics - first law of thermodynamics - limitations of first law - concept of internal energy – second law of thermodynamics - concept of entropy.
THERMODYNAMIC RELATIONS : Introduction - Helmholtz free energy function - Gibbs free energy function - co-efficient of volumetric expansion – isothermal compressibility - differential relation for U, H, G & F - Maxwell relations.

UNIT II
GENERALIZED RELATIONS : Generalized relation for Cp, Cv, K  - relations for internal energy and enthalpy -the various Tds equation - clapeyron equation - gas tables - enthalpy and internal energy - pressure ratio - volume ratio - change of entropy – Introduction to third law of thermodynamics.
EXERGY : Introduction - availability of heat - availability of a closed system - availability function of the closed system - availability of steady flow system – availability function of open system.

UNIT III
IRREVERSIBILITY : Introduction - irreversibility for closed and open system - steady flow process - effectiveness - second law analysis of the power plant.
NON RELATIVE GAS MIXTURES : Introduction - basic definitions for gas mixtures - PVT relations ship for mixtures of ideal gases - properties of mixtures of ideal gases - entropy change due to mixing - mixtures of perfect gases at different initial pressure and temperatures.

UNIT IV
GAS POWER CYCLES: Introduction - air standard cycles - Carnot cycle - Otto cycle - diesel cycle - dual cycles - comparison between Otto, diesel, dual cycles - variations between the air standard Otto cycle and actual cycle - Sterling cycle - Erickson cycle – Atkinson cycle - Bray ton cycle - Lenoir cycle.

UNIT V
DIRECT ENERGY CONVERSION : Introduction - thermoelectric converters - thermo-ionic converters magneto hydrodynamics generators - solar power cells plant – fuel cells hydrogen - hydrogen fuel cells - direct and indirect oxidation fuel cells- biochemical fuels cells.

Suggested Assignment:
To refer Elsevier Publishers Journal of Applied Thermal Engineering for giving a seminar on any current topic of relevance.

REFERENCE BOOKS:
1. Advanced Thermodynamics: Van Wyllan , TMGH
2. Engineering Thermodynamics: P.K.Nag, TMGH
3. Advanced Thermodynamics: Ray & Sarao, Central Publishers.

COMPUTATIONAL METHODS IN THERMAL ENGINEERING

UNIT-I
Review of basic fluid mechanics and the governing (Navier-Stokes) equations, Techniques for solutions of PDEs.

UNIT-II
Finite difference method (FD), finite element method and finite volume method. Finite volume (FV) method in one-dimension, Differencing schemes, steady and unsteady calculations

UNIT-III
Boundary conditions, FV discretization in two and three dimensions, SIMPLE algorithm and flow field calculations, variants of SIMPLE, Introduction to Turbulence and turbulence modeling, illustrative flow computations

UNIT-IV
Introduction to commercial software’s FLUENT and CFX – grid generation, flow prediction and post-processing Application of FD methods for unsteady and steady heat conduction problems.

UNIT-V
GLOBAL MODELLING UNDER DYNAMIC CONDITIONS: numerical methods for integrating ordinary differential equations and systems of equations; use of EES software; applications to systems with thermal storage, mass storage, etc.

Suggested Assignment:
To refer ASME Series of Journal of Heat Transfer, Journal of Fluids Engineering, Journal of Thermal Science and Engineering Applications  Elsevier Publishers Journal of Applied Thermal Engineering, Journal of Finite Elements in Analysis and Design for giving a seminar on any current topic of relevance.

TEXT BOOKS:
1. K.Muralidhar and T.Sundararajan, "Computational Fluid Flow and Heat Transfer", Narosa Publishing House ,New Delhi1995.
2. P.S., Ghoshdasdidar, "Computer Simulation of flow and heat transfer" TMH Ltd., 1998.
3. S.V. Patankar, "Numerical heat transfer fluid flow", Hemisphere Publishing Co, 1980.
4. D.A. Anderson, I.I. Tannehill, and R.H. Pletcher, Computational Fluid Mechanics and Heat Transfer, Hemishphere Publishing Corporation, New York, USA, 1984.
5. C.A.J. Fletcher, ,"Computational Techniques for Fluid Dynamics - Fundamental and General Techniques, Springer-Verlag,1987.
6. T.K. Bose, "Numerical Fluid Dynamics" Narosa Publishing House, 1997.
7. T.K. Sengupta, Fundamentals of Fluid Dynamics, University Press, Hyderabad.


THERMAL SYSTEMS SIMULATION AND DESIGN

AIM: To provide review and use knowledge from thermodynamics, heat transfer and fluid
mechanics, modeling and simulation techniques for thermal system component analysis
and their synthesis in integral engineering systems and processes

OBJECTIVES:
 To learn basic principles underlying piping, pumping, heat exchangers; modeling and optimization in design of thermal systems. To develop representational modes of real processes and systems. To optimization concerning design of thermal systems.

UNIT I
DESIGN CONCEPTS
Design Principles , Workable Systems , Optimal Systems , Matching of System
Components , Economic Analysis , Depreciation , Gradient Present Worth factor.

UNIT II
MATHEMATICAL MODELLING
Equation Fitting , Nomography , Empirical Equation , Regression Analysis , Different
Modes of Mathematical Models , Selectio n, Computer Programmes for Models.
UNIT III
MODELLING THERMAL EQUIPMENTS
Modelling Heat Exchangers , Evaporators , Condensers , Absorption and Rectification
Columns, Compressors, Pumps, Simulation Studies, Information Flow Diagram
, Solution Procedures.

UNIT IV
OPTIMIZATION
Objective Function Formulation , Constraint Equations , Mathematical Formulation ,
Calculus Method , Dynamic Programming , Search Methods , ANN and Genetic
Algorithm.
UNIT V
DYNAMIC BEHAVIOUR
Steady state Simulation , Laplace Transformation , Feedback Control Loops , Stability
Analysis , Non-Linearities.

Suggested Assignment:
To refer ASME Series of Journal of Heat Transfer, Elsevier Publishers Journal of Applied Thermal Engineering, AIAA Transactions of Journal of Energy for giving a seminar on any current topic of relevance.
TEXT BOOKS:
1. Stoecker W. F., Design of Thermal Systems , McGraw Hill Edition , 1989.
2. Bejan A., George Tsatsaronis , Michael J. Moran , Thermal Design and Optimization ,
Wiley , 1996.
REFERENCES:
1. Kaput J. N., Mathematical Modelling , Wiley Eastern Ltd , New York , 1989.
2. Yogesh Jaluria , Design and Optimization of Thermal Systems , CRC Press , 2007.
3. Rao S. S., Engineering Optimization Theory and Practice , New Age Publishers ,
2000.

COMBUSTION AND EMISSION IN ENGINES
AIM
 To Demonstrate extensive mastery of the fundamental principles which govern the design and operation of internal combustion engines as well as a sound technical framework for understanding real world problems.
OBJECTIVE :
Understand combustion in spark ignition and diesel engines.
To identify the nature and extent of the problem of pollutant formation and control
in internal combustion engines government legislation.
UNIT I
COMBUSTION PRINCIPLES                                            
Combustion – Combustion equations, heat of combustion - Theoretical flame temperature - chemical equilibrium and dissociation - Theories of Combustion - Pre-flame reactions - Reaction rates - Laminar and Turbulent Flame Propagation in Engines.

UNIT II
COMBUSTION IN S.I. ENGINE                                                        
Initiation of combustion, stages of combustion, normal and abnormal combustion, knocking combustion, pre-ignition, knock and engine variables, features and design consideration of combustion chambers. Flame structure and speed, Cycle by cycle variations, Lean burn combustion, stratified charge combustion systems. Heat release correlations. After treatment devices for SI engines.    

UNIT III
COMBUSTION IN C.I. ENGINE                      
Stages of combustion, vaporization of fuel droplets and spray formation, air motion, swirl measurement, knock and engine variables, features and design considerations of combustion chambers, delay period correlations, heat release correlations, Influence of the injection system on combustion. Direct and indirect injection systems. Afer treatment devices for diesel enignes.  
UNIT IV
COMBUSTION IN GAS TURBINES                                              
Flame stability, re-circulation zone and requirements - Combustion chamber configuration, materials.      
UNIT V  
EMISSIONS                                                  
Main pollutants in engines, Kinetics of NO formation, NOx formation in SI and CI engines. Unburned hydrocarbons, sources, formation in SI and CI engines,  Soot formation and oxidation, Particulates in diesel engines, Emission control measures for SI and CI engines, Effect of emissions on Environment and human beings.
Suggested Assignment:
To refer SAE Transactions International Journal of Engines, International Journal of Fuels and Lubrications for giving a seminar on any current topic of relevance.


TEXT BOOKS :
Ramalingam, K.K.,  Internal Combustion Engines, Scitech Publications (India) Pvt.  Ltd.,  2004.
Ganesan, V, Internal Combustion Engines,  Tata McGraw Hill Book Co.,  2003.
John B.Heywood, Internal Combustion Engine Fundamentals,McGraw Hill Book,  1998

REFERENCES :
Mathur,M.L., and Sharma,R.P.,  A Course in Internal  Combustion  Engines, Dhanpat  Rai  Publications  Pvt.   New Delhi-2,  1993.
Obert,E.F.,  Internal Combustion Engine and Air Pollution, International Text Book Publishers,  1983.
Cohen,H, Rogers,G,E.C, and Saravanamuttoo,  H.I.H.,  Gas Turbine Theory, Longman Group Ltd.,  1980.

COMPUTATIONAL FLUID DYNAMICS

UNIT I
Introduction: Basic tools of CFD, Numerical Vs experimental tools. ; Mathematical Behavior of PDEs: Parabolic, Hyperbolic and Elliptic PDEs.

UNIT II
Methodology of CFDHT: Discrete representation of flow and heat transfer domain: Grid generation, Governing equations and boundary conditions based on FVM/FDM, Solution of resulting set of linear algebraic equations, Graphical representation and analysis of qualitative results, Error analysis in discretization using FVM/FDM.

UNIT III
Solution of 1-D/2-D steady/unsteady: Diffusion problems, Convection problems, Convection-diffusion problems, source term linearization. ; Explicit and Implicit Approach: Explicit and implicit formulation of unsteady problems,

UNIT IV
Stability analysis. ; Solution of Navier-Stokes Equations for Incompressible Flows: Staggered and collocated grid system, SIMPLE and SIMPLER algorithms. ;

UNIT V
Special Topics in CFDHT: Numerical Methodology for Complex Geometry, Multi-block structured grid system, Solution of phase change Problems.

Suggested Assignment:
To refer ASME Series of Journal of Fluids Engineering for giving a seminar on any current topic of relevance.

TEXT BOOK:
1. S.V. Patankar, Numerical Heat Transfer and Fluid Flow, Taylor and Francis, ISBN-10: 0891165223.

REFERENCES:
1. H. K. Versteeg and W. Malalasekra, Introduction to Computational Fluid Dynamics: The Finite Volume Method, Prentice Hall (2nd Edition), ISBN-10: 0131274988.
2. Jr. D. A. Anderson, Computational Fluid Mechanics and Heat Transfer by McGraw-Hill Education
3. M. N. Ozisik, Finite Difference Method, CRC (1st Edition).



ADVANCED OPTIMIZATION TECHNIQUES
UNIT I
Linear programming: Two-phase simplex method, Big-M method, duality, interpretation, applications.
Assignment problem: Hungarian’s algorithm, Degeneracy, applications, unbalanced problems, traveling salesman problem.

UNIT II
Classical optimization techniques: Single variable optimization with and without constraints, multi – variable optimization without constraints, multi – variable optimization with constraints – method of Lagrange multipliers, Kuhn-Tucker conditions.
Numerical methods for optimization:  Nelder Mead’s Simplex search method, Gradient of a function, Steepest descent method, Newton’s method, types of penalty methods for handling constraints.

UNIT III
Genetic algorithm (GA) : Differences and   similarities between conventional and evolutionary algorithms, working principle, reproduction, crossover, mutation, termination criteria, different reproduction and crossover operators, GA for constrained optimization, draw backs of GA,

UNIT IV
Genetic Programming (GP): Principles of genetic programming, terminal sets, functional sets, differences between GA & GP, random population generation, solving differential equations using GP.
Multi-Objective GA: Pareto’s analysis, Non-dominated front, multi – objective GA, Non-dominated sorted GA, convergence criterion, applications of multi-objective problems .

UNIT V
Applications of Optimization in Design and Manufacturing systems: Some typical applications like optimization of path synthesis of a four-bar mechanism, minimization of weight of a cantilever beam, optimization of springs and gears, general optimization model of a machining process, optimization of arc welding parameters, and general procedure in optimizing machining operations sequence.  

Suggested Assignment:
To refer ASME Series of Journal of Engineering Materials and Technology, Journal of Mechanical Design, Elsevier Publishers Finite Elements in Analysis and Design, Simulation modeling Practice and Theory for giving a seminar on any current topic of relevance.


Text Books:
1. Optimal design – Jasbir Arora, Mc Graw Hill (International) Publishers
2. Optimization for Engineering Design – Kalyanmoy Deb, PHI Publishers
3. Engineering Optimization – S.S.Rao, New Age Publishers

References:
1.Genetic algorithms in Search, Optimization, and Machine learning – D.E.Goldberg, Addison-Wesley Publishers
2. Genetic Programming- Koza
3. Multi objective Genetic algorithms - Kalyanmoy Deb, PHI Publishers


THEORY OF METAL CUTTING AND TOOL DESIGN

UNIT I
Mechanics of Metal Cutting: Geometry of Metal Cutting Process, Chip formation, Chip Thickness ratio, radius of chip curvature, cutting speed, feed and depth of cut - Types of Chips, Chip breakers.
Orthogonal and Oblique cutting processes-definition, Forces and energy calculations (Merchant’s Analysis).- Power consumed – MRR – Effect of Cutting variables on Forces, Force measurement using Dynamometers.

UNIT II
Single Point Cutting Tool: Various systems of specifications, single point cutting tool geometry and their inter-relation. Theories of formation of built-up edge and their effect, design of single point contact tools throwaway inserts.

UNIT III
Multipoint Cutting Tools: Drill geometry, design of drills, Rake & Relief angles of twist drill, speed, feed and depth of cut, machining time, forces, milling cutters, cutting speed & feed – machining time – design - from cutters.
Grinding: Specifications of grinding of grinding wheel, mechanics of grinding, Effect of Grinding conditions on wheel wear and grinding ratio. Depth of cut, speed, machining time, temperature, power.

UNIT IV
Tool Life and Tool Wear: Theories of tool wear-adhesion, abrasive and diffusion wear mechanisms, forms of wear, Tool life criteria and machinability index.
Types of sliding contact, real area of contact, laws of friction and nature of frictional force in metal cutting. Effect of Tool angle, Economics, cost analysis, mean co-efficient of friction.

UNIT V
Cutting Temperature: Sources of heat in metal cutting, influence of metal conditions. Temperature distribution, zones, experimental techniques, analytical approach. Use of tool work thermocouple for determination of temperature. Temperature distribution in Metal Cutting

Suggested Assignment:
To refer ASME Series of Journal of Manufacturing Science and Engineering, Springer Publishers  International Journal of Advanced Manufacturing Technology for giving a seminar on any current topic of relevance.

REFERENCES:
1. Metal Cutting Principles - M C Shaw / Oxford and IBH Publications, New Delhi
2. Fundamentals of Machining - Boothryd / Edward Amold publishers Ltd.
3. Metal cutting theory and cutting tool design -V. Arshinov and G. Alekseev / Mir Publishers, Moscow
4. Fundamentals of Metal cutting and Machine tools -B.L.Juneja, G. S. Sekhom and Nitin Seth / New Age International publishers

METAL FORMING PROCESSES
UNIT I
Fundamentals of Metal Forming: Classification of forming processes, mechanism of metal forming, temperature of metal working, hot working, cold working, friction and lubricants. Rolling of metals: Rolling processes, forces and geometrical relationship in rolling, simplified analysis, rolling load, rolling variables, theories of cold and hot rolling, problems and defects in rolling, torque and power calculations.

UNIT II
Forging: Classification of forging processes, forging of plate, forging of circular discs, open die and closed-die forging, forging defects, and powder metallurgy forging. Extrusion: Classification, Hot Extrusion, Analysis of Extrusion process, defects in extrusion, extrusion of tubes, production of seamless pipes.

UNIT III
Drawing: Drawing of tubes, rods, and wires: Wire drawing dies, tube drawing process, analysis of wire, deep drawing and tube drawing. Sheet Metal forming: Forming methods, Bending, stretch forming, spinning and Advanced techniques of Sheet Metal Forming, Forming limit criteria, defect in formed parts.

UNIT IV
Advanced Metal forming processes: HERF, Electromagnetic forming, residual stresses, in process heat treatment, computer applications in metal forming. Press tool design: Design of various press tools and dies like piercing dies, blanking dies, compound dies and progressive blanking dies, design of bending, forming and drawing dies.

UNIT V
Jigs and Fixture design: Principles of location, six-point location principle, clamping elements and methods.

Suggested Assignment:
To refer ASME Series of Journal of Manufacturing Science and Engineering, Springer Publishers  International Journal of Advanced Manufacturing Technology SAE Transactions International Journal of Materials and Manufacturing for giving a seminar on any current topic of relevance

Reference Books:
1. Mechanical Metallurgy / G.E. Dieter / Tata McGraw Hill
2. Principles of Metal Working / Sunder Kumar
3. Jig and Fixture Design – Edward G. Hoffman, Thomson
4. Principles of Metal Working processes / G.W. Rowe
5. ASM Metal Forming Hand book.

RAPID PROTOTYPING AND TOOLING
UNIT I
INTRODUCTION    
Need - Development of RP systems – RP process chain - Impact of Rapid Prototyping and Tooling on Product Development – Benefits- Applications – Digital prototyping - Virtual prototyping.

UNIT II
LIQUID BASED AND SOLID BASED RAPID PROTOTYPING SYSTEMS                                                                      
Stereolithography Apparatus, Fused deposition Modeling, Laminated object manufacturing, Three dimensional printing: Working Principles, details of processes, products, materials, advantages, limitations and applications - Case studies.

UNIT III
POWDER BASED RAPID PROTOTYPING SYSTEMS            
Selective Laser Sintering, Direct Metal Laser Sintering, Three Dimensional Printing, Laser Engineered Net Shaping, Selective Laser Melting, Electron Beam Melting:  Processes, materials, products, advantages, applications and limitations – Case Studies.

UNIT IV
REVERSE ENGINEERING AND CAD MODELING            
Basic concept- Digitization techniques – Model Reconstruction – Data Processing for Rapid Prototyping: CAD model preparation, Data Requirements – geometric modeling techniques: Wire frame, surface and solid modeling – data formats - Data interfacing, Part orientation and support generation, Support structure design, Model Slicing and contour data organization, direct and adaptive slicing, Tool path generation.

UNIT V
RAPID TOOLING          
Classification: Soft tooling, Production tooling, Bridge tooling; direct and indirect – Fabrication processes, Applications. Case studies - automotive, aerospace and electronic industries.                

Suggested Assignment:
To refer ASME Series of Journal of Manufacturing Science and Engineering, Springer Publishers  International Journal of Advanced Manufacturing Technology SAE Transactions International Journal of Materials and Manufacturing for giving a seminar on any current topic of relevance

TEXT BOOKS:
Rapid prototyping: Principles and applications, second edition, Chua C.K., Leong K.F., and Lim C.S., World Scientific Publishers, 2003.
Rapid Tooling: Technologies and Industrial Applications, Peter D.Hilton, Hilton/Jacobs, Paul F.Jacobs, CRC press, 2000.
REFERENCES:
Rapid prototyping, Andreas Gebhardt, Hanser Gardener Publications, 2003.
Rapid Prototyping and Engineering applications : A tool box for prototype development, Liou W.Liou, Frank W.Liou,  CRC Press, 2007.
Rapid Prototyping: Theory and practice, Ali K. Kamrani, Emad Abouel Nasr, Springer, 2006
NON - DESTRUCTIVE EVALUATION

UNIT I
Ultra Sonic Hardness Testing: Flaw Detection Using Dye Penetrants. MagneticParticle Inspection introduction to electrical impedance, Principles of Eddy Current testing, Flaw detection using eddy currents.
Introduction to X-Ray Radiography: The Radiographic process, X-Ray and Gamma-ray sources, Geometric Principles, Factors Governing Exposure, Radio graphic screens, Scattered radiation, Arithmetic of exposure, Radiographic image quality and detail visibility, Industrial X-Ray films,

UNIT II
X-Ray Radiography processes: Fundamentals of processing techniques, Process control, The processing Room, Special Processing techniques, Paper Radiography, Sensitometric characteristics of x-ray films, Film graininess signal to noise ratio in radiographs, The photographic latent image, Radiation Protection,

UNIT III
Introduction to Ultrasonic Testing: Generation of ultrasonic waves, Horizontal and shear waves, Near field and far field acoustic wave description, Ultrasonic probes straight beam, direct contact type, Angle beam, Transmission/reflection type, and delay line transducers, acoustic coupling and media,

UNIT IV
Ultrasonic tests: Transmission and pulse echo methods, A-scan, B-scan, C-scan,F-scan and P-scan modes, Flaw sizing in ultrasonic inspection: AVG, Amplitude, Transmission, TOFD, Satellite pulse, Multi-modal transducer, Zonal method using focused beam. Flow location methods, Signal processing in Ultrasonic NDT; Mimics, spurious echos and noise. Ultrasonic flaw evaluation.

UNIT V
Holography: Principles and practices of Optical holography, acoustical, microwave, x-ray and electron beam holography techniques.
Applications - I: NDT in flaw analysis of Pressure vessels, piping
Applications - II: NDT in Castings, Welded constructions, etc., Case studies.

Suggested Assignment:
To refer ASTM Series of Journal of Testing and Evaluation for giving a seminar on any current topic of relevance.

TEXT BOOKS:
1. Ultrasonic testing by Krautkramer and Krautkramer
2. Ultrasonic inspection & Training for NDT : E. A. Gingel, Prometheus Press,
3. ASTM Standards, Vol 3.01, Metals and alloys

QUALITY ENGINEERING AND MANUFACTURING
UNIT-I
Quality value and Engineering: An overall quality system, quality engineering in production design, quality engineering in design production processes.
Loss function and quality level: Derivation and use of quadratile loss function, economic consequences of tightening tolerances as a means to improve quality, evaluations and types tolerances (N-type-, S-type and L-type)

UNIT-II
Tolerance Design and Tolerancing: Functional limits, tolerance design for N-type, L-type and S-type characteristics, tolerance allocation for multiple components.
Parameter and tolerance design: Introduction to parameter design, signal to noise ratios, parameter design strategy, Introduction to tolerance design, tolerance design using the loss function, identification of tolerance design factors.

UNIT-III
Design of Experiments: Introduction, Task aids and Responsibilites for DOE process steps, DOE process steps description.
Analysis of variance (ANOVA): no-WAY anova, One-way ANOVA, two-way ANOVA,  Critique of F-test, ANOVA for four level factors, multiple level factors.

UNIT-IV
Orthogonal Arrays: Typical test strategies, better test strategies, efficient test strategies, conducting and analyzing an experiment.

UNIT-V
Interpolation of experimental results: Interpretation methods, percent contribution, estimating the mean.
ISO-9000 Quality system, BDRE,6-sigma, bench marking, quality circles-brain storming fishbone diagram-problem analysis.

Suggested Assignment:
To refer ASME Series of Journal of Manufacturing Science and Engineering, Springer Publishers  International Journal of Advanced Manufacturing Technology SAE Transactions International Journal of Materials and Manufacturing for giving a seminar on any current topic of relevance

REFERENCE BOOKS:
Taguchi techniques for quality engineering/Philip J.Ross / McGraw Hill Intl. 2nd Edition.
Quality Engineering in Production systems/G.Taguchi, A.Elasayed et al/Mc.Graw Hill Intl. Edition.
Taguchi methods explained: Practical steps to Robust Design/Papan P.Bagchi/Prentice Hall Ind. Pvt. Ltd. New Delhi.

MECHANICS AND MANUFACTURING METHODS OF COMPOSITES
Unit I
Basic concepts and characteristics: Geometric and Physical definitions, natural and man-made composites, Aerospace and structural applications, types and classification of composites.
Reinforcements: Fibres- Glass, Silica, Kevlar, carbon, boron, silicon carbide, and born carbide fibres. Particulate composites, Polymer composites, Thermoplastics, Thermosetts, Metal matrix and ceramic composites.

Unit II
Micromechanics: Unidirectional composites, constituent materials and properties, elastic properties of a lamina, properties of typical composite materials, laminate characteristics and configurations. Characterization of composite properties.

Unit  III
Coordinate transformations: Hooke’s law for different types of materials, Hooke’s law for two dimensional unidirectional lamina, Transformation of stress and strain, Numerical examples of stress strain transformation, Graphic interpretation of stress – strain relations. Off - axis, stiffness modulus, off - axis compliance.

Unit IV
Elastic behavior of unidirectional composites: Elastic constants of lamina, relationship between engineering constants and reduced stiffness and compliances, analysis of laminated composites, constitutive relations.
Strength of unidirectional lamina: Micro mechanics of failure, Failure mechanisms, Strength of an orthotropic lamina, Strength of a lamina under tension and shear maximum stress and strain criteria, application to design. The failure envelope, first ply failure, free-edge effects. Micro mechanical predictions of elastic constants.

Unit V
Analysis of laminated composite plates  
Introduction, thin plate theory, specially orthotropic plate, cross and angle ply laminated plates, problems using thin plate theory.                
Manufacturing methods: Autoclave, tape production, moulding methods, filament winding, man layup, pultrusion, RTM.
                                                                             
Suggested Assignment:
To refer ASTM Series of Journal of Composites, Technology and Research and ASTM        e-news for giving a seminar on any current topic of relevance.


Text Books:
1. R. M. Jones, Mechanics of Composite Materials, Mc Graw Hill Company, New  York,
   1975.
2. Engineering Mechanics of Composite Materials by Isaac and M.Daniel, Oxford  
    University Press, 1994.
References:
1. B. D. Agarwal and L. J. Broutman, Analysis and performance of fibre  Composites,
    Wiley-Interscience, New York, 1980.
2. L. R. Calcote, Analysis of Laminated Composite Structures, Van Nostrand Rainfold,
   New York, 1969.



PAPER II


CAD THEORY AND PRACTICE
UNIT I
CAD TOOLS:
Definition of CAD Tools, Types of system, CAD/CAM system evaluation criteria, brief treatment of input and output devices. Graphics standard, functional areas of CAD, Modeling
and viewing, software documentation, efficient use of CAD software.

GEOMETRICMODELLING:
Types of mathematical representation of curves, wire frame models wire frame entities parametric representation of synthetic curves her mite cubic splines Bezier curves B-splines rational curves

UNIT II
SURFACE MODELING :
Mathematical representation surfaces, Surface model, Surface entities surface representation,
Parametric representation of surfaces, plane surface, rule surface, surface of revolution,
Tabulated Cylinder.
PARAMETRIC REPRESENTATION OF SYNTHETIC SURFACES –
Hermite Bi-cubic surface, Bezier surface, B- Spline surface, COONs surface, Blending
surface , Sculptured surface, Surface manipulation – Displaying, Segmentation, Trimming,
Intersection, Transformations (both 2D and 3D).

UNIT III
GEOMETRICMODELLING-3D:
Solid modeling, Solid Representation, Boundary Representation (B-rep), Constructive Solid
Geometry (CSG).
CAD/CAM data Exchange: Evaluation of data – exchange format, IGES data representations
and structure, STEP Architecture, implementation, ACIS & DXF.

UNIT IV
DESIGN APPLICATIONS:
Mechanical tolerances, Mass property calculations, Finite Element Modeling and Analysis
and Mechanical Assembly.

UNIT V
Collaborative Engineering: Collaborative Design, Principles, Approaches,
Tools, Design Systems.

Suggested Assignment:
To refer ASME Series of Journal of Tribology, Journal of Mechanical Design for giving a seminar on any current topic of relevance.



REFERENCES :
1. CAD/CAM Theory and Practice / Ibrhim Zeid / Mc Graw Hill international.
2. Mastering CAD/CAM / Ibrhim Zeid / Mc Graw Hill international.
3. CAD/CAM / P.N.Rao / TMH.
4. CAD CAM: Principles, Practice and Manufacturing Management / Chris Mc Mohan,
Jimmie Browne / Pearson edu. (LPE)
5. Concurrent Engineering Fundamentals: Integrated Product Development/ Prasad /
Prentice Hall.
6. Successful Implementation of Concurrent Product and Process / Sammy G Sinha /
Wiley, John and Sons Inc..



EXPERIMENTAL STRESS ANALYSIS

UNIT I
Introduction: Theory of Elasticity, Plane stress and plane strain conditions,  Compatibility conditions. Problems using plane stress and plane strain conditions, Threedimensional stress strain relations.
Strain Measurement Methods: Various types of strain gauges, Electrical Resistance strain gauges, semiconductor strain gauges, strain gauge circuits

UNIT II
Recording Instruments: Introduction, static recording and data logging, dynamic recording at very low frequencies, dynamic recording at intermediate frequencies, dynamic recording at high frequencies, dynamic recording at very high frequencies, telemetry systems.
Brittle coatings: Introduction, coating stresses, failure theories, brittle coating crack patterns, crack detection, ceramic based brittle coatings, resin based brittle coatings, test procedures for brittle coatings analysis, calibration procedures, analysis of brittle coating
data.

UNIT III
Moire Methods: Introduction, mechanism of formation of Moire fringes, the geometrical approach to Moire-Fringe analysis, the displacement field approach to Moire- Fringe analysis, out of plane displacement measurements, out of plane slope measurements, sharpening and multiplication of Moire-Fringes, experimental procedure and techniques.

UNIT IV
Photo elasticity: Photo elasticity – Polariscope – Plane and circularly polarized light, Bright and dark field setups, Photo elastic materials – Isochromatic fringes – Isoclinics
Three dimensional Photo elasticity : Introduction, locking in model
deformation, materials for three-dimensional photo elasticity, machining cementing and slicing three-dimensional models, slicing the model and interpretation of the resulting fringe patterns, effective stresses, the shear-difference method in three dimensions, applications of the Frozen-stress method, the scattered-light method.

UNIT V
Birefringent Coatings Introduction, Coating stresses and strains, coating sensitivity, coating materials, application of coatings, effects of coating thickness, Fringe order determinations in coatings, stress separation methods.

Suggested Assignment:
To refer ASME Series of Journal of Tribology, Journal of Mechanical Design, Journal of Turo Machinery, Journal of Dynamic Systems Measurement and Control for giving a seminar on any current topic of relevance.

References:
1. Theory of Elasticity by Timoshenke and Goodier Jr
2. Experimental stress analysis by Dally and Riley,Mc Graw-Hill
3. A treatise on Mathematical theory of Elasticity by LOVE .A.H
4. Photo Elasticity by Frocht

ADVANCED MECHANICAL VIBRATIONS
UNIT I
Introduction: Characterization of engineering vibration problems, Review of single degree freedom systems with free, damped and forced vibrations
Two-degree of Freedom Systems: Principal modes of vibration, Spring coupled and mass coupled systems, Forced vibration of an undamped close coupled and far coupled systems, Undamped vibration absorbers, Forced damped vibrations, Vibration isolation.

UNIT II
Multi-degree Freedom systems: Eigen-value problem, Close coupled and far coupled systems, Orthogonality of mode shapes, Modal analysis for free, damped and forced vibration systems, Approximate methods for fundamental frequency- Rayleigh’s, Dunkerely, Stodola and Holzer method, Method of matrix iteration, Finite element method for close coupled and far coupled systems.

UNIT III
Free and forced vibration of continuous elastic systems. Longitudinal vibration of rods. The effects of boundaries and discontinuities on longitudinal vibration transmission. Phase closure principle and natural frequencies.

UNIT IV Transient Vibrations: Response to an impulsive, step and pulse input, Shock spectrum
Non-linear Vibrations: Non-linear systems, Undamped and forced vibration with non-linear spring forces, Self-excited vibrations.

UNIT V
Flexural vibration of beams: Derivation of the equation of motion and the procedure to obtain free vibration solutions. Introduction to forced response (harmonic).

Suggested Assignment:
To refer ASME Series of Journal of Vibration and Acoustics, Journal of Mechanical Design for giving a seminar on any current topic of relevance.

Text Books:
Theory and practice of Mechanical Vibrations J.S. Rao and K. Gupta New Age International
Mechanical Vibrations (3rd edition), S.S. Rao, Addiston Wesley
Mechanical Vibrations G.K. Groover Nem Chand & Brothers
Mechanical Vibration Practice V. Ramamurti Narosa Publications
Mechanical Vibrations V.P. Singh Dhanpat Rai & sons
Textbook of Mechanical Vibrations R.V. Dukkipati & J. Srinivas Prentice Hall of India

SIMULATION AND MODELLING
UNIT I
System – ways to analyze the system – Model - types of models – Simulation – Definition – Types of simulation models – steps involved in simulation – Advantages & Disadvantages. Parameter estimation – estimator – properties – estimate – point estimate – confidence interval estimates – independent – dependent – hypothesis – types of hypothesis- steps – types 1& 2 errors – Framing – strang law of large numbers.

UNIT II
Building of Simulation model – validation – verification – credibility – their timing – principles of valid simulation Modeling – Techniques for verification – statistical procedures
for developing credible model. Modeling of stochastic input elements – importance – various procedures – theoretical distribution – continuous – discrete – their suitability in modeling.

UNIT III
Generation of random variates – factors for selection – methods – inverse transform – composition – convolution – acceptance – rejection – generation of random variables – exponential – uniform – weibull – normal Bernoullie – Binomial – uniform – poisson

UNIT IV
Simulation languages – comparison of simulation languages with general purpose languages
– Simulation languages vs Simulators – software features – statistical capabilities – G P S S –
SIMAN- SIMSCRIPT –Simulation of M/M/1 queue – comparison of simulation languages.

UNIT V
Output data analysis – Types of Simulation w.r.t output dat analysis – warmup period- Welch
algorithm – Approaches for Steady – State Analysis – replication – Batch means methods – comparisons. Applications of Simulation – flow shop system – job shop system – M/M/1 queues with infinite and finite capacities – Simple fixed period inventory system – Newboy paper problem.

Suggested Assignment:
To refer Elsevier Publishers Journal of Simulation Modeling Practice and Theory and ASME  Journal of Mechanical Design for giving a seminar on any current topic of relevance.

Text books:
1. Simulation Modelling and Analysis, Law, A.M.& Kelton, McGraw Hill, 2nd Edition, New York.
2. Discrete Event System Simulation, Banks J. & Carson J.S., PH, Englewood Cliffs, NJ.
3. Simulation of Manufacturing Systems, by Carrie A., Wiley, NY.
4. A Course in Simulation, Ross, S.M., McMillan, NY.
5. Simulation Modelling and SIMNET, Taha H.A., PH, Englewood Cliffs, NJ

DESIGN OF HYDRAULIC AND PNEUMATIC SYSTEMS
AIM
 To impart knowledge on the Design of Hydraulic and Pneumatic Systems as practiced in industries.
OBJECTIVE
 To study the principles, practices and techniques of Design of Hydraulic and Pneumatic Systems.
UNIT I
OIL HYDRAULIC SYSTEMS            
Hydraulic Power Generators - Selection and specification of pumps, pump characteristics - Linear and Rotary Actuators - selection, specification and characteristics - Pressure - direction and flow control valves - relief valves, non-return and safety valves - Hydraulic actuation systems.
UNIT II
HYDRAULIC CIRCUIT DESIGN            
Reciprocation, quick return, sequencing, synchronizing circuits - accumulator circuits - industrial circuits – press circuits - hydraulic milling machine - grinding, planning, copying, forklift, earth mover circuits – Design and methodology-Sequential circuits, cascade, circuits - Compound and combination circuit design - selection of components - safety and emergency mandrels.
UNIT III
PNEUMATIC SYSTEMS AND CIRCUITS                          
Pneumatic fundamentals - control elements, position and pressure sensing -logic circuits - switching circuits - fringe conditions - modules and their integration.
UNIT IV
PNEUMATIC CIRCUIT DESIGN              
Sequential circuits - cascade methods - mapping methods – step counter method - compound circuit design - combination circuit design - hydro pneumatic circuits  - Pneumatic equipments - selection of components - design calculations –application.
UNIT V
COMPUTER CONTROL &MAINTENANCE OF FLUID POWER CIRCUITS:
Fuzzy logic in fluid power circuits- PLC in fluid powers- PLC ladder diagram – Low cost automation - Robotic circuits - Installation -Fault finding in fluid power circuits.

Suggested Assignment:
To refer ASME Series of Journal of Tribology, Journal of Mechanical Design, Journal of Pressure Vessel Technology for giving a seminar on any current topic of relevance.

TEXTBOOK:
Antony Espossito, “Fluid power with Applications ", Prentice Hall, 1980.

REFERENCES:
Dudleyt, A.Pease and John J.Pippenger, " Basic Fluid Power ", Prentice Hall, 1987.
Andrew Parr, " Hydraulic and Pneumatics ", (HB), Jaico Publishing House, 1999.
Bolton. W. “Pneumatic and Hydraulic Systems ", Butterworth - Heineman, 1997.





DESIGN OF PUMPS AND COMPRESSORS

UNIT I
Introduction to pumps and compressors. Characteristics of working fluids, Fluid mechanics concepts and governing laws of fluid flow.

UNIT II
Pumps – various components and their functions. Classification of pumping systems – based on the applications and working fluids. Design of pumps – data required for the design of pump and design calculations. Selection of the drive – Types of drives, their behavior and advantages, Selection of the pumps – types of pumps. Selection of piping and other components. Development of a schematic layout of the piping system.

UNIT III
Operation and maintenance – installation of pumping system. Testing of the pumping systems – Various methods based on the working fluid, drive and pump etc., Maintenance of the pumps – Prediction and correction methods, Factors affecting the maintenance and their evaluation.

UNIT IV
Rotary compressor system – various components and their functions. Classification of compressors. Design of compressor – data and analysis. Characteristics of the compressors. Selection of the drive and compressors. Development of the schematic layout of the compressor system.

UNIT V
Design of impeller, Types of impellers – centrifugal and axial. Design of a diffuser – Vaneless and vaned diffuser. Types of casings, casing design. Performance characteristics of turbo compressors.

Suggested Assignment:
To refer ASME Series of Journal of Tribology, Journal of Mechanical Design, Journal of Pressure Vessel Technology for giving a seminar on any current topic of relevance.

Text Books:

1. S.M. Yahya, Turbines, Compressors and Fans, Tata McGraw Hill Publishing Co.
2. Val.S. Lobanoff and Robert R. Ross, Centrifugal Pumps – Designs and Application, Jaico book publishing Co.

THEORY OF PLASTICITY

UNIT I
Iinvariance in terms of the deviatoric stresses, representative stress - Engineering and natural
strains, cubical dilation, finite strains co-efficients, Octahedral strain, strain rate and the strain
rate tensor.

UNIT II
Yield criteria for ductile metal - Yield criteria for an anisotropic material. Stress – Strain
Relations – Plastic stress-strain relations, Prandtl Roeuss Saint Venant, Levy – Von Mises,
Yield locus, symmetry convexity, normality rule.

UNIT III
Application to problems, simple forms of indentation problems using upper bounds.
Problems of metal forming.

UNIT IV
Crystal Plasticity, the crystalline state, crystallographic indices, the preferential planes and
directions, critical shear stress, theory of simultaneous slip, slip bands, the plastic bending in
crystals, dislocations and crystal growth, polycrystals and grain boundaries,

UNIT V
Plane plastic strain and the theory of the slip line filed, two dimensional problems of steady
and non steady motion, plastic anisotropy.

Suggested Assignment:
To refer ASME Series of Journal of Tribology, Journal of Mechanical Design, Journal of Pressure Vessel Technology for giving a seminar on any current topic of relevance.

REFERENCES:
1. Narayanasamy R, “Theory of Engineering Plasticity”, Ahuja Publications, 2000.
2. Johnson and Mellor, “Plasticity for Mechanical Engineers”, Ban Nostrand, 1973..
3. R.Hill , “The Mathematic theory of Plasticity”, Oxford Publication, 1982.


ELECTRIC AND HYBRID VEHICLES
AIM :
OBJECTIVE: To understand working of different configurations of electric vehicles, and
its components, hybrid vehicle configuration and performance analysis.
UNIT  I
ELECTRIC VEHICLES                                                                        
Introduction,  Components, vehicle mechanics – Roadway fundamentals, vehicle kinetics, Dynamics of  vehicle motion - Propulsion System Design.  
UNIT II
BATTERY                                                                                                    
Basics – Types, Parameters – Capacity, Discharge rate, State of charge, state of Discharge, Depth of Discharge, Technical characteristics, Battery pack Design, Properties of Batteries.
UNIT III
DC  & AC ELECTRICAL MACHINES            
Motor and Engine rating,  Requirements, DC machines , Three phase A/c machines,  Induction machines,  permanent  magnet machines, switched reluctance machines.
UNIT IV
ELECTRIC VEHICLE DRIVE TRAIN                                                        
Transmission configuration, Components – gears, differential, clutch, brakes regenerative braking, motor sizing.
UNIT V
HYBRID ELECTRIC VEHICLES                                                              
Types – series, parallel and series, parallel configuration – Design – Drive train, sizing of components
Suggested Assignment:
To refer SAE Transactions International Journal of Engines, International Journal of Fuels and Lubricants, International Journal of Passenger Cars-Electronic & Electrical Systems for giving a seminar on any current topic of relevance.

REFERENCES :
1. Iqbal Hussain, Electric  & Hybrid  Vechicles – Design Fundamentals, CRC Press.
2. Rand D.A.J, Woods, R & Dell RM Batteries for Electric vehicles.



DESIGN OF HEAT TRANSFER EQUIPMENT

UNIT I
DESIGN OF HEAT EXCHANGERS:
Exchangers-mean temperature differences for parallel and counter flow- effectiveness method(N.T.U)-keys and London charts.
DESIGN OF CONDENSERS:
Types overall heat transfer coefficients- temperature distribution and heat flow in a condenser-pressure drop in a condenser –extended fin surfaces-consideration of fouling factor-L.M.T.D. correction factor.

UNIT II
DESIGN OF EVAPORATORS TYPES:
Temperature distribution and heat flow in an evaporator-pressure drop- factor to be consider in the design of heat transfer equipment-types of heat consideration of fouling factor –correction factor
DESIGN OF COOLING ROWERS AND SPRAY PONDS:
Classification-performance of cooling towers – analysis of counter flow cooling towers-enthalpy- temperature diagram of air and water- cooling ponds- types of cooling ponds – cross flow cooling towers- procedure for calculation of outlet conditions.

UNIT III
DESIGN OF COMPRESSORS:
Types-equivalent shaft work-volumetric efficiency-factors affecting total volumetric efficiency –compound compression with inter cooling- rotary compressors-surging.

UNIT IV
DESIGN OF DUCTS:
Continuity equation-Bernoulli’s equation-pressure losses-frictional charts- coefficient of resistance for fillings- duct sizing methods.

UNIT V
DESIGN OF FANS:
Standard air-fan horsepower-fan efficiency-similarity laws-fan laws-performance coefficients- theoretical expression for total pressure drop by a fan-centrifugal fan- axial flow fan-system resistance.
PIPING SYSTEM:
Requirements of a good piping system-pressure drop in pipes-moody chart-refrigerant piping-discharge line-liquid line-suction line-piping arrangement

Suggested Assignment:
To refer ASME Series of Journal of Heat Transfer for giving a seminar on any current topic of relevance.

REFERENCES:
1. Heat and mass transfer by Arora & Domkundwar.
2. Refrigeration & Air-Conditioning by P.L.Ballaney
3. .Refrigeration & Air-Conditioning by C.P.Arora.
4. .Refrigeration & Air-Conditioning by Stoecker

REFRIGERATION EQUIPMENT AND CONTROLS

UNIT I
Compressors - types - equivalent shaft work - Volumetric efficiency – factors affecting total volumetric efficiency - compound compression with inters cooling - rotary compressors - surging - screw compressors - lubricating oils. Condensers - types -Water cooled Condensers-Air cooled, Evaporative types - Economic water rate - Economic water velocity - over all heat transfer co-efficient - design - temperature distribution and heat flow in a condenser - pressure drop - fouling factor - LMTD correction factor.

UNIT II
Cooling towers and spray ponds - classification - performance of cooling towers - analysis of counter flow cooling towers - enthalpy - temperature diagram of air and water - cooling ponds - types - cross flow cooling towers - procedure for calibration of outlet conditions.

UNIT III
Evaporators - types - Flooded and dry Evaporators, natural and forced convection type - shell and tube - shell and coil, plate type - secondary Evaporators – temperature distribution and heat flow in evaporator - pressure drop - fouling correction factor Defrosting - necessity - methods - manual, automatic, periodic defrosting, solid and liquid adsorbents, water defrosting, defrosting by reversing the cycle, automatic hot gas defrosting, thermo balance defrosting, electric control defrosting.

UNIT IV
Expansion devices - Capillary tube, thermostatic expansion valve - float valves, externally equalized valves - automatic expansion valves - solenoid control valve - location of piping and pump design consideration.

UNIT V
Performance of complete Vapour compression system-Performance of condensing unit-compressor -Evaporator-balancing of load in two stage compression. Installation of vapour compression refrigeration system - evaluation and dehydration testing for leakages - charging - adding oil.

Suggested Assignment:
To refer Elsevier Publishers International Journal of Refrigeration for giving a seminar on any current topic of relevance.

REFERENCES:
1.’Refrigeration and Air Conditioning’- by Stoecker – TMGH– International Edition
2. ’Refrigeration and Air Conditioning’ - by Domkundwar – Dhanpat Rai & Co.
3. ‘Refrigeration and Air Conditioning’ - by - C.P.Arora – TMGH
4. ASHRAE Guide and Data book applications.


I.C. ENGINES AND ALTERNATE FUELS

UNIT I
ntroduction: Historical Review –Broad classification of fuels - Engine Types – Design and operating Parameters. Cycle Analysis: Thermo-chemistry of Fuel – Air mixtures, properties – Ideal Models of Engine cycles – Real Engine cycles difference and Factors responsible for – Computer Modeling and simulation of combustion process.

UNIT II
Gas Exchange Processes: Volumetric Efficiency – Flow through ports – Supercharging and Turbo charging. Exhaust gas recirculation system and their designing. Charge Motion: Mean velocity and Turbulent characteristics – Swirl, Squish – Pre chamber Engine flows. Fuel supply systems for SI and CI engines to use gaseous fuels like LPG, CNG, and Hydrogen.

UNIT III
Engine Combustion: Combustion and Speed – Cyclic Variations – Ignition – Abnormal combustion Fuel factors. Combustion in CI engines: Essential Features – Types of Cylinders. Pr. Data – Fuel Spray Behavior – Ignition Delay – Mixing Formation and control:

UNIT IV
Pollutant Formation and Control: Nature and extent of problems – Nitrogen Oxides, Carbon monoxide, Unburnt Hydrocarbon and particulate emission – Measurement – Exhaust Gas Treatment. Catalytic converter, 2 way type & 3 way type.

UNIT V
Modern Trends in IC Engines: Computer Simulation and Optimized Design –Lean Burning and Adiabatic concepts - Rotary Engines. Modification in IC Engines to suite Bio-Fuels.

Suggested Assignment:
To refer SAE Transactions International Journal of Engines, International Journal of Fuels and Lubricants, International Journal of Passenger Cars-Electronic & Electrical Systems for giving a seminar on any current topic of relevance.

REFERENCES:
1. I.C. Engines Fundamentals/Heywood/Mc Graw Hill
2. I.C. Engines /Ferguson
3. I.C. Engines / Maleev
4. IC Engines / V Ganesan
5. I.C. Engine in theory and Practice Vol. I and II / Taylor
6. I.C. Engines / Obert / Int.Text Book Co.
7. Combustion Engine Processes / Lichty
8. Scavenging of two stroke Cycle Engines / Switzer


THERMAL AND NUCLEAR POWER PLANTS

UNIT I
Energy scenario. Overview of steam power plant. Analysis of steam cycles. Feedwater heaters. De-aerator and drain cooler. Optimization of cycle parameters, reheat and regeneration. Analysis of multi-fluid coupled cycles. Cogeneration of power and process heat. Combined cycle power generation.

UNIT II
Fuels. Combustion mechanisms. Draft systems. Combustion control. Furnaces for burning coal in fluidized beds and in pulverized form. Coal handling installation.
Different types of boilers and their specific uses. Boiler mountings and accessories. Feedwater treatment.

UNIT III
Boiler maintenance. Circulation theory. Downcomers and risers. Drum and its internals. Economiser. Convective and radiant super heaters. Superheat temperature control. Recuperative and regenerative air preheaters. Dust and ash removal systems. Environmental aspects of power generation

UNIT IV
Basic concepts of reactor physics, radioactivity. Neutron Scattering. Thermal and fast reactors. Nuclear cross-sections. Neutron flux and reaction rates. Moderator criteria. Reactor core design. Conversion and breeding. Types of reactors. Characteristics of boiling water, pressurized water, pressurized heavy water, gas cooled and liquid metal cooled reactors.

UNIT V
Future trends in reactor design and operation. Thermal-hydraulics of reactors. Heavy water management. Containment system for nuclear reactor. Reactor safety radiation shields. Waste management. Indian nuclear power programme.

Suggested Assignment:
To refer Inderscience Publishers International Journal of Nuclear Science and Technology, ASME Series of Journal of Thermal Science and Engineering Applications for giving a seminar on any current topic of relevance.

Text BookS:
M.M.EI. Wakil., ‗Nuclear Power Engineering’, McGraw Hill Book Company, New York, 1987.
S. Glasstone and A. Setonske., ‗Nuclear Reactors, Engineering‘, 3rd Ed., CBS Publishers and Distributors, 1992.

ReferenceS:
Loftness, ‗Nuclear Power Plants’, D. Van Nostrand Company Inc, Princeton, 1964.
S. Sarg et al., ‗Physics of Nuclear Reactors’, Tata McGraw Hill Publishing Company Ltd., 1985.
T. J. Connoly., ‗Fundamentals of Nuclear Energy’, John Wiley, 1978.

EXPERIMENTAL METHODS IN THERMAL ENGINEERING

UNIT I
Introduction: Basic concepts of measurement methods, single and multi point measurement Min space and time. Processing of experimental data, curve fitting and regression analysis. Data Acquisition systems: Fundamentals of digital signals and their transmission, A/D-and D/A converters, Basic components of data acquisition system. Computer interfacing of digital instrument and data acquisition systems; Digital multiplexes, Data acquisition board (DAQ), Digital image processing fundamentals.

UNIT II
Design and Construction of Experimental facilities: wind tunnel, general test rigs, Test cells for flow visualization and temperature mapping.      
Modeling and Simulation of Measurement System: Lumped analysis, first order and second order systems: Frequency response and time constant calculation. Response of a generalized instrument to random data input, FFT analysis.

UNIT III
Temperature Measurement: Measurement Design, Construction and Analysis of liquid and gas thermometers, resistance thermometer with wheat stone bridge, Thermo-electric effect, Construction, testing and calibration of thermocouples and thermopiles, Analysis of effect of bead size and shielding on time constant and frequency response,  characteristics of thermocouple, pyrometers, radiation thermometers.
Interferometry & Humidity measurement:  interferometers, Humidity measurement: Conventional methods, electrical transducers, Dunmox humidity and microprocessor based dew point instrument, Calibration of humidity sensors.

UNIT IV
Flow and Velocity Measurement: industrial flow measuring devices, design, selection and calibration, velocity measurements, pitot tubes, yaw tubes, pitot static tubes; frequency response and time constant calculation. Hot-wire anemometer; 2d/3d flow measurement and turbulence measurement, Laser application in flow measurement, Flow visualization techniques, Combustion photography.
UNIT V
Measurement of Pressure, Force, and Torque: Analysis of liquid manometer, dynamics of variable area and inclined manometer, Pressure transducers, Speed and torque measurement: speed and torque measurement of rotating system.
Air Pollution sampling and measurement; Units for pollution measurement, gas sampling technique s, particulate sampling technique, gas chromatography.

Suggested Assignment:
To refer ASME Series of Journal of Thermal Science and Engineering Applications, Journal of Fluids Engineering and AIAA Transactions Journal of Thermo physics and Heat Transfer, Journal of Energy for giving a seminar on any current topic of relevance.


REFERENCES:
Experimental Methods for Engineers - J.P. Holman, McGraw-Hill Publications.
Mechanical Measurements - Beckwith M.G., Marangoni R.D. and Lienhard J.H.,Pearson Education.
Measurements systems-Application and Design - E.O. Doebelin, Tata McGraw-Hill, Publications.

ELECTRONIC ENGINE MANAGEMENT SYSTEMS
AIM:
To teach the students about the various sensors and engine management systems used in petrol and diesel engines
OBJECTIVE :
To give an in-depth knowledge of various sensors used in engine management
To give an overview of different types of fuel injection and ignition systems
To know the latest technological advancements in vehicle power plant
UNIT I
ELECTRONICS                                                                                                            
Semiconducters , Transistors, Amplifiers – Integrated circuits – Analog and Digital, Logic
Gastes, Microcontrollers –Analog Digital / Digital Analog Converters.
UNIT II
SENSORS                                        
Sensors for Air flow, Pressure, Temperature, Speed, Exhaust Oxygen, Knock and Position in engine management systems – Principle of operation, construction and characteristics.    

UNIT III
GASOLINE INJECTION SYSTEM                                        
Open loop and closed loop systems, Mono point, Multi point, Direct injection systems and Air assisted systems – Principles and Features, examples of Bosch injection systems. Idle speed, lambda, knock and spark timing control. Three way catalytic converters, Lean NOx converters.    
UNIT IV
DIESEL INJECTION SYSTEM                                          
Heat release in the diesel engine and need for control of fuel injection. Inline injection pump - Rotary Pump and injector– Construction and principle of operation, Electronic control of these pumps. Common rail and unit injector system – Construction and principle of operation,
UNIT V
IGNITION SYSTEMS                                          
Ignition fundamentals, solid state ignition systems, high energy ignition distributors, Electronic spark timing and control. Combined ignition and fuel management systems.  Dwell angle calculation, Ignition timing calculation.

Suggested Assignment:
To refer SAE Transactions International Journal of Engines, International Journal of Fuels and Lubricants, International Journal of Passenger Cars-Electronic & Electrical Systems for giving a seminar on any current topic of relevance.

TEXT BOOKS:
Robert N.Brady,  Automotive Computers and Digital Instrumentation,  Prentice Hall,   1988.
Bosch Technical Instruction Booklets.
Tom Denton, Automotive Electrical and Electronic Systems, Edward Amold, 1995.
REFERENCES:
1. Duffy Smith, Auto Fuel Systems, The Good Heart Willcox Company Inc., Publishers,   1987.
2. Gasoline Engine Management,  Second Edition, Robert Bosch GmbH, 2004.
3. Engine Management, Second Edition, Robert Bosch GmbH, 1999.
4. Eric Chowaniety, Automobile Electronics, SAE Publications 1995.
5. William B. Ribbews, Understanding Automotive Electronics, Fifth Edition, SAE  
            Publications1998.

INTELLIGENT MANUFACTURING SYSTEMS

UNIT I
Computer Integrated Manufacturing Systems – Structure and functional areas of CIM system
- CAD, CAPP, CAM, CAQC, ASRS. Advantages of CIM. Manufacturing Communication Systems – MAP/TOP, OSI Model, Data Redundancy, Top down and Bottom-up Approach, Volume of Information. Intelligent Manufacturing – System Components, System Architecture and Data Flow, System Operation.

UNIT II
Components of Knowledge Based Systems – Basic Components of Knowledge Based Systems, Knowledge Representation, Comparison of Knowledge Representation Schemes, Interference Engine, Knowledge Acquisition. Machine Learning – Concept of Artificial Intelligence, Conceptual Learning, Artificial Neural Networks - Biological Neuron, Artificial Neuron, Types of Neural Networks, Applications in Manufacturing.

UNIT III
Automated Process Planning – Variant Approach, Generative Approach, Expert Systems for
Process Planning, Feature Recognition, Phases of Process planning.

UNIT IV
Knowledge Based System for Equipment Selection (KBSES) – Manufacturing system design, Equipment Selection Problem, Modeling the Manufacturing Equipment Selection Problem, Problem Solving approach in KBSES, Structure of the KBSES.

UNIT V
Group Technology: Models and Algorithms – Visual Method, Coding Method, Cluster Analysis Method, Matrix Formation – Similarity Coefficient Method, Sorting-based Algorithms, Bond Energy Algorithm, Cost Based method, Cluster Identification Method, Extended CI Method. Knowledge Based Group Technology - Group Technology in Automated Manufacturing System, Structure of Knowledge based system for group technology (KBSGT) – Data Baswe, Knowledge Base, Clustering Algorithm.

Suggested Assignment:
To refer ASME Series of Journal of Manufacturing Science and Engineering, Springer Publishers  International Journal of Advanced Manufacturing Technology SAE Transactions International Journal of Materials and Manufacturing for giving a seminar on any current topic of relevance

Text Books:
1. Intelligent Manufacturing Systems by Andre Kusaic.
2. Artificial Neural Networks by Yagna Narayana
3. Automation, Production Systems and CIM by Groover M.P.
4. Neural Networks by Wassarman.

LOGISTICS AND SUPPLY CHAIN MANAGEMENT
UNIT I
Logistics and Competitive Strategy: Competitive advantage through logistic – Mission – Integrated supply chains – Models in Logistics Management – Logistics to supply Chain Management – Focus areas in supply Chain Management – performance Measures for SCM. Customer Service Dimension: The marketing and logistics interface – Customer service and customer retention - Service driven logistics systems – Basic service capability – Increasing customer expectations – Value added services – Customer satisfaction and success – Time based logistics.

UNIT II
Logistics System Design: Logistics positioning – Logistics reengineering – reengineering procedure – logistics environmental assessment – time based logistics – alternative logistics strategies – strategic integration – logistics time based control techniques. Measuring Logistics Costs and Performance: The concept of Total Cost analysis – Principles of logistics costing – Logistics and the bottom line – Impact of Logistics on Shareholder value – customer profitability analysis – direct product profitability – cost driver and activity based costing.

UNIT III
Logistics and Supply chain relationships: Benchmarking the logistics process and SCM operation – Mapping the supply chain processes – Supplier and distributor benchmarking – setting benchmarking priorities – identifying logistics performance indicators – Channel structure – Economics of distribution – channel relationship – logistic service alliances.

UNIT IV
Sourcing, transporting and pricing products: Sourcing decisions – transportation in the supply chain – basic transportation economics and pricing – transportation documentation – pricing and revenue management in the supply chain – pricing and revenue management in supply chains.

UNIT V
Coordination and Technology in Supply chain: Lack of coordination and Bullwhip Effect – obstacles to coordination – managerial levers to achieve coordination – Building strategic partners and trust within a supply chain. Role of IT in the supply chain – Ebusiness. Managing global logistics and global supply chains: Logistics in a global economy – global operating levels – interlink global economy – Global supply chain business processes – Global strategy, purchasing, logistics – Global alliances – Issues and Challenges.

Suggested Assignment:
To refer Elsevier Publishers International Journal of Computers and Industrial Engineering Springer Publishers Journal of Industrial Engineering International for giving a seminar on any current topic of relevance



References:
1. Donald J. Bowersox and David J. Closs, Logistical Management: The Integrated Supply Chain Process, TMH.
2. Martin Christopher, Logistics Supply Chain Management, Pitman, London.
3. Sunil Chopra and Peter Meindl: Supply Chain Management: Strategy, Planning and Operation, Pearson Education, New Delhi.
4. B.S.Sahay, supply Chain Management for Global competitivesness, Macmillan.
5. Philip B.Schary, Tage Skjott – Larsen: Manageing the Global Supply Chain.
6. Arjun J Van Weele: Purchasing and Supply Chain Management- Analysis, Planning and Practice, Thomson Learning.
7. Ballou, Business Logistics/Supply chain management, Pearson Education.

ADVANCES IN MANUFACTRURING TECHNOLOGY
AIM:
The aim of this course is to impart knowledge in various fields of advanced manufacturing technology
OBJECTIVE:
At the end of this course the students are expected to understand metal cutting and cutting tool materials, special machining processes, unconventional machining processes, micro machining process and rapid prototyping.
UNIT I
METAL CUTTING AND TOOL MATERIALS                                                  
Orthogonal and oblique cutting – types of tool wear, abrasion, diffusion, Oxidation. Fatigue and adhesive wear – Prediction of tool life – Monitoring of wear, Cutting forces and Vibration – tool Materials, Cemented Carbide, Coated Carbide, Cermets. Ceramic, CBN and PCD – Selection of Machining parameters and Tools.
UNIT II
SPECIAL MACHINING PROCESSES & EXPERIMENTAL TECHINIQUES
Deep hole drilling Honing – Lapping – Super finishing – Burnishing – Broaching  High speed Machining, Measurement of cutting forces, temperature, Vibration  and Tool wear in machining processes.
UNIT III  
UNCONVENTIONAL MACHINING                                                            
Principles, Processes. Various influencing parameters and Applications of Ultrasonic Machining, Electro Discharge Machining, Electro Chemical Machining, Electron and Laser Beam Machining, Plasma Arc Machining and Water Jet Machining.
UNIT IV  
MICRO MACHINING              
Introduction to MEMS, principle, process capabilities, types, advantages, limitations and applications of bulk micro machining, surface micro machining and tool based micro machining processes.




UNIT V
RAPID PROTOTYPING                                                                                
Introduction – Classification – Principle advantages limitations and applications- Stereo lithography – laminated object manufacturing – Selective laser sintering –FDM, SGC, 3D Printing.
Suggested Assignment:
To refer ASME Series of Journal of Manufacturing Science and Engineering, Springer Publishers  International Journal of Advanced Manufacturing Technology SAE Transactions International Journal of Materials and Manufacturing for giving a seminar on any current topic of relevance.

TEXT BOOKS:
Shaw Milton.C., “Metal Cutting Principles”, Second Edition, Oxford University,  Press, 2005.
2.   Armarego E.J.A. and Brown R.H., “The Machining of metals”, Prentice Hall,  1982.  
REFERENCES:
1.    Battacharya, “ theory of metal cutting”, NCB Agency, 1984.
2.    HMT Manual, “Non – t5raditional Machining Methods”,  1975.
3.    Pandley P.S. and shah.N. “Modern Manufacturing Processes”, 1980.
4.    Sadasivan T.A., and Sarathy.D. “cutting Tools for Productive Machining”,  Widia  
       ( India) Limited 1999.
5.   Rich F. and Knight’K., “Artificial Intelligence”, McGraw Hill Inc, 1991.
6.   Marc J. Madou, Fundamentals of Microfabrication: The Science of   Miniaturization,    
      Second Edition, CRC Press (ISBN: 0849308267), 2006.

PRODUCTION AND OPERATIONS MANAGEMENT
UNIT I
Operation Management – Definition – Objectives – Types of production systems – historical development of operations management – Current issues in operation management. Product design – Requirements of good product design – product development – approaches – concepts in product development – standardization - simplification – Speed to market – Introduction to concurrent engineering.

UNIT II
Value engineering – objective – types of values –function & cost – product life cycle – steps in value engineering – methodology in value engineers – FAST Diagram –Matrix Method. Location – Facility location and layout – Factors considerations in Plant location – Comparative Study of rural and urban sites – Methods of selection plant layout – objective of good layout – Principles – Types of layout – line balancing.

UNIT III
Aggregate Planning – definition – Different Strategies – Various models of Aggregate Planning-Transportation and graphical models Advance inventory control systems push systems –Material Requirement – Terminology – types of demands – inputs to MRP- techniques of MRP – Lot sizing methods – benefits and drawbacks of MRP – Manufacturing Resources Planning (MRP –II). Pull systems – Vs Push system – Just in time (JIT) philosophy Kanban System - Calculation of number of Kanbans Requirements for implementation JIT – JIT Production process – benefits of JIT.

UNIT IV
Scheduling – Policies – Types of scheduling- Forward and Backward Scheduling – Gantt Charts – Flow shop Scheduling – n jobs and 2 machines, n jobs and 3 machines – Job shop Scheduling – 2 jobs and n machines – Line of Balance.

UNIT V
Project Management – Programming Evaluation Review Techniques (PERT) – three times estimation – critical path – probability of completion of project – critical path method - crashing of simple nature.

Suggested Assignment:
To refer Elsevier Publishers Journal of Operations Management, International Journal of Production Economics for giving a seminar on any current topic of relevance

REFERENCES:
1. “Operations Management” by E.S. Buffs.
2. “Operations Management, Theory and Problems” by Joseph G. Monks.
3. “Production Systems Management” by James. L. Riggs.
4. “Production and Operations Management” by Chary.
5. “Operation Management” by Chase
6. “Production & Operation Management” by PannerSelvam
7. “Production & Operation Analysis” by Nahima

ADVANCES IN CASTING AND WELDING PROCESSES
AIM:
To impart knowledge on basic concepts and advances in casting and welding processes.
OBJECTIVES:
To study the metallurgical concepts and applications of casting and welding process.
To acquire knowledge in CAD of casting and automation of welding process.

UNIT   I
CASTING DESIGN
Heat transfer between metal and mould –– Design considerations in casting – Designing for directional solidification and minimum stresses - principles and design of gating and risering
UNIT   II
CASTING METALLURGY        
Solidification of pure metal and alloys – shrinkage in cast metals – progressive and directional solidification –– Degasification of the melt-casting defects – Castability of  steel , Cast Iron, Al alloys , Babbit alloy and Cu alloy.
UNIT  III
RECENT TRENDS IN CASTING AND FOUNDRY LAYOUT        
Shell moulding, precision investment casting, CO2 moulding, centrifugal casting, Die casting, Continuous casting, Counter gravity low pressure casting, Squeeze casting and semisolid processes. Layout of mechanized foundry – sand reclamation – material handling in foundry pollution control in foundry –– Computer aided design of casting.
UNIT   IV
WELDING METALLURGY AND DESIGN      
Heat affected Zone and its characteristics – Weldability of steels, cast iron, stainless steel, aluminum, Mg , Cu , Zirconium and titanium alloys – Carbon Equivalent of Plain and alloy steels Hydrogen embrittlement – Lamellar tearing – Residual stress – Distortion and its control . Heat transfer and solidification - Analysis of stresses in welded structures – pre and post welding heat treatments – weld joint design – welding defects – Testing of weldment.

UNIT   V
RECENT TRENDS IN WELDING      
Friction welding, friction stir welding – explosive welding – diffusion bonding – high frequency induction welding – ultrasonic welding – electron beam welding – Laser beam welding –Plasma welding – Electroslag welding- narrow gap, hybrid twin wire active TIG – Tandem MIG-  modern brazing and soldering techniques – induction, dip resistance, diffusion processes – Hot gas, wave and vapour phase soldering.  Overview of automation of welding in aerospace, nuclear, surface transport vehicles and under water welding.

Suggested Assignment:
To refer Springer Publishers  Welding International, American Foundry Society Publishers  International Journal of Metal Casting for giving a seminar on any current topic of relevance

REFERENCES:
ASM Handbook, Vol 15, Casting, 2004
ASM Handbook vol.6, welding Brazing & Soldering, 2003
Parmer R.S., Welding Engineering and Technology, Khanna Publishers,2002
Srinivasan N.K., Welding Technology, Khanna Tech Publishers, 2002
HEINELOPER & ROSENTHAL, Principles of Metal Casting, Tata McGraw Hill, 2000.
Jain P.L., Principles of Foundry Technology,Tata McGrawHill Publishers, 2003
Carrry B., Modern Welding Technology, Prentice Hall Pvt Ltd., 2002
IOTROWSKI – Robotic welding – A guide to selection and application – Society of mechanical Engineers, 1987.
SCHWARIZ, M.M. – Source book on innovative welding processes – American Society for Metals (OHIO), 1981
CORNU.J. Advanced welding systems – Volumes I, II and III, JAICO Publishers, 1994.
LANCASTER.J.F. – Metallurgy of welding – George Alien & Unwin Publishers, 1980


MATERIALS TECHNOLOGY
UNIT I
Elasticity in metals and polymers, mechanism of plastic deformation, role of dislocations, yield stress, shear strength of perfect and real crystals, strengthening mechanism, work hardening, solid solution, grain boundary strengthening. Poly phase mixture, precipitation, particle, fiber and dispersion strengthening, effect of temperature, strain and strain rate on plastic behavior, super plasticity, deformation of non crystalline material.

UNIT II
Griffth’s Theory, stress intensity factor and fracture Toughness, Toughening Mechanisms, Ductile and Brittle transition in steel, High Temperature Fracture, Creep, Larson : Miller Parameter, Deformation and Fracture mechanism maps. Fatigue, Low and High cycle fatigue test, Crack Initiation and Propagation mechanism and Paris Law, Effect of surface and metallurgical parameters on Fatigue, Fracture of non:metallic materials, fatigue analysis, Sources of failure, procedure of failure analysis.

UNIT III
Motivation for selection, cost basis and service requirements, Selection for Mechanical Properties, Strength, Toughness, Fatigue and Creep. Selection for Surface durability, Corrosion and Wear resistance, Relationship between Materials Selection and Processing, Case studies in Materials Selection with relevance to Aero, Auto, Marine, Machinery and Nuclear Applications.

UNIT IV
MODERN METALLIC MATERIALS : Dual Phase Steels, Micro alloyed, High Strength Low alloy (HSLA) Steel, Transformation induced plasticity ( TRIP) Steel, Maraging Steel, Intermetallics, Ni and Ti Aluminides, Smart Materials, Shape Memory alloys, Metallic Glass, Quasi Crystal and Nano Crystalline Materials.

UNIT V
NONMETALLIC MATERIALS : Polymeric materials and their molecular structures, Production Techniques for Fibers, Foams, Adhesives and Coatings, Structure, Propertiesand Applications of engineering Polymers, Advanced Structural Ceramics WC, TiC, TaC, Al2 O3, SiC, Si3 N4 , CBN and Diamond : properties, Processing and applications.

Suggested Assignment:
To refer ASME Series of Journal of Engineering Materials and Technology, SAE Transactions International Journal of Materials and Manufacturing for giving a seminar on any current topic of relevance.

TEXT BOOKS:
1. Mechanical Behaviour of Materials / Thomas H. Courtney, McGraw Hill.
2. Mechanical Metallurgy / George E. Dieter / McGraw Hill.
3. Selection and use of Engineering Materials /Charles J.A/ Butterworth Heiremann.


STATISTICAL QUALITY CONTROL
OBJECTIVE:
This course is concerned with the applications of statistical tools in measuring
and controlling the quality of products/processes.
UNIT I
QUALITY FUNDAMENTALS
Importance of quality, meaning of quality, quality dimensions, quality planning, quality
control, SQC, Quality assurance, quality costs, economics of quality, quality and
productivity, quality and reliability, quality loss function.
UNIT II
CONTROL CHARTS FOR VARIABLES
Process variation,– Statistical basis, 3 – sigma control limits, Rational sub-grouping, X ,R
and S charts, Interpretation of charts, warning and modified control limits, operating
characteristic curve for X – chart, SPC -process capability analysis – Cp, CPK, Cpm,
Machine capability, Gauge capability.
UNIT III
CONTROL CHARTS FOR ATTRIBUTES
P, np, C, U and ku charts, demerits control chart, Multi – variable chart, individual
measurement charts – moving average and moving range charts, quality control in service
sector.
UNIT IV
ACCEPTANCE SAMPLING
Need for Acceptance sampling, economics of sampling, sample selection, single and
Double sampling – O.C. curves, Average outgoing quality (AOQ), Average sample
Number (ASN), Average total inspection (ATI), Multiple and sequential sampling, sampling
plans – military standards, Dodge – Roming, IS 2500.
UNIT V
METROLOGY & INSPECTION
Fundamental methods of measurement, precision & accuracy, measurement devices -
Linear and Angular - Coordinate Measuring Machine, Destructive and Non- Destructive
Testing methods.


Suggested Assignment:
To refer Springer Publishers Journal of Industrial Engineering International, Elsevier Publishers Computers and Industrial Engineering for giving a seminar on any current topic of relevance.


TEXT BOOK :
1. Douglus C.Montgomery, Introduction to Statistical Quality Control, John Wiley &
Sons, 2004.
REFERENCES :
1. Statistical Quality Control, Eugene L.Grant and Richard S.Leaven Worth, TMH,
Seventh Edition, 2000.
2. Quality Control. Dale H.Besterfield, Pearson Education Asia, Seventh
Edition,2004.